research Is The Metabolism Of Testosterone To 5α-Dihydrotestosterone Required For Androgen Action In The Skin?
Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
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research A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice
RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
research Novel Progestogenic Androgens for Male Contraception: Design, Synthesis, and Activity of C7 Alpha-Substituted Testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research Postmenopausal Virilization Due to a Rare Left Ovarian Androgen-Secreting Leydig Cell Tumor Identified by Ovarian Vein Sampling
A woman's masculine symptoms were caused by a rare tumor in her left ovary, which was found using a special blood test.
research Androgen Receptors and Androgen-Dependent Initiation of Protein Synthesis in the Prostate
Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.
research Novel Adenosine Triphosphate-Binding Cassette, Subfamily A, Member 12 Mutations Associated with Congenital Ichthyosiform Erythroderma
New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.
research The Cycle Characteristics and Outcomes of Infertile Nonclassic 21-Hydroxylase Deficiency Patients Undergoing Ovarian Stimulation for In Vitro Fertilization
Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.
research Virilizing Ovarian Steroid Cell Tumor in a 40-Year-Old South Indian Female: A Case Report
A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
research The Role of Testosterone in SARS-CoV-2 Infection
Low testosterone levels may lead to more severe COVID-19 outcomes.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Hair Follicles and Associated Glands as Androgen Targets
Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
research Sex Steroid Synthesis in Human Skin In Situ: The Roles of Aromatase and Steroidogenic Acute Regulatory Protein in the Homeostasis of Human Skin
Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
research Society for Endocrinology Guidelines for Testosterone Replacement Therapy in Male Hypogonadism
Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
research Androgen Treatment of Postmenopausal Women
Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research Is Seborrhea a Sign of Autonomic Impairment in Parkinson's Disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia
Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.
research Receiver Operating Characteristic Analysis of the Performance of Basal Serum Hormone Profiles for the Diagnosis of Polycystic Ovary Syndrome in Epidemiological Studies
Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research How Should Postmenopausal Androgen Excess Be Evaluated?
Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
research Clinical, Ultrasound, and Hormonal Markers of Androgenicity in Acne Vulgaris
Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
research Effective Medical Treatment for Common Baldness in Women
Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
research Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Changes in Androgen Levels in Menopausal Women
Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.