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UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Most HIV patients develop skin symptoms that can indicate the stage of their disease.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Skin issues can indicate immune system problems.

Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Microbes might play a role in vitiligo.

Higher levels of certain immune cells and proteins are linked to more severe lupus symptoms.

Current research explores hair growth drugs, while future research aims for personalized treatments.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

Early regulatory T cells are crucial for normal skin pigmentation.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Janus kinase inhibitors show promise in treating alopecia areata but need more safety research.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Permanent hair dye may cause total hair loss.

Targeting Vδ1+T-cells may help treat alopecia areata.

Immune cells are essential for skin regeneration using biomaterial scaffolds.

CD80CD86 deficiency causes hair loss by disrupting regulatory T cells.