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    Glossary T-cell receptor complex

    group of proteins on T-cells recognizing specific antigens

    The T-cell receptor complex is a group of proteins found on the surface of T-cells, a type of white blood cell. This complex allows T-cells to recognize and bind to specific antigens (foreign substances) presented by other cells, which is crucial for the immune system to identify and respond to infections or abnormal cells, such as those found in cancer.

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    1. Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders MedComm · 2026
    2. Multiplex matrix network analysis of protein complexes in the human TCR signalosome Science Signaling · 2016 · 32 citations
    3. Epidermal growth factor receptor/mitogen-activated kinase inhibitor treatment induces a distinct inflammatory hair follicle response that includes collapse of immune privilege British Journal of Dermatology · 2024 · 4 citations
    4. Folliculotropic Mycosis Fungoides with Skewed T-cell Receptor CDR3 Motif: Suggestive of Lipid-antigen Selection? Acta Dermato Venereologica · 2017 · 3 citations
    5. Entdeckung von Autoantigenen bei der Haarverluststörung Alopecia areata: Implikation von posttranslationalen Modifikationen Karger Kompass. Dermatologie · 2023
    6. Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations Frontiers in immunology · 2022 · 21 citations
    7. Alopecia Areata: An Overview of the Disease and its Genetic Basis: Review Article The Egyptian Journal of Hospital Medicine · 2022 · 1 citations
    8. INVESTIGATING THE MECHANISMS UNDERLYING THE PATHOGENESIS OF ALOPECIA AREATA White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York) · 2018
    9. HYPOPIGMENTED MYCOSIS FUNGOIDES IN A CHILD SUCCESSFULLY TREATED WITH UVA1-LIGHT Pediatric Dermatology · 2005 · 14 citations
    10. Epithelial-to-Mesenchymal Stem Cell Transition in a Human Organ: Lessons from Lichen Planopilaris Journal of Investigative Dermatology · 2017 · 71 citations
    11. CUTANEOUS T-CELL LYMPHOMA Dermatologic Clinics · 2001 · 11 citations
    12. 056 IL-15 prolongs hair growth and operates as a guardian of human hair follicle immune privilege Journal of Investigative Dermatology · 2022
    13. 1405 Cellular and molecular characterization of sebaceous gland self-renewal and regeneration following complete genetic ablation Journal of Investigative Dermatology · 2023
    14. <i>In vivo </i>CD44‐CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance European Journal of Immunology · 2006 · 33 citations
    15. High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata JCI insight · 2018 · 46 citations
    16. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016 · 64 citations
    17. Current management strategies for cutaneous T-cell lymphoma Clinics in Dermatology · 2004 · 39 citations
    18. Complex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy Journal of Investigative Dermatology · 2014 · 12 citations
    19. Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis American journal of human genetics · 2019 · 53 citations
    20. Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease Cell Reports · 2025 · 4 citations
    21. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    22. TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells Research Square (Research Square) · 2023
    23. 572 Development of immunotherapies targeting TCR-Vβ2 for treatment of cutaneous T cell lymphoma Journal of Investigative Dermatology · 2024
    24. The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding Receptors · 2024
    25. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    26. 455 Molecular correlation with clinical outcomes in an open label clinical trial of oral tofacitinib in patients with alopecia areata Journal of Investigative Dermatology · 2018 · 1 citations
    27. TYK2 Inhibition with Deucravacitinib Improves Clinical Outcomes and Resolves Interferon-Driven Inflammation in Lichen Planopilaris 2026
    28. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    29. Deciphering the Complex Immunopathogenesis of Alopecia Areata International Journal of Molecular Sciences · 2024 · 45 citations
    30. Immunological aspects and gender bias during respiratory viral infections including novel Coronavirus disease‐19 (COVID‐19): A scoping review Journal of Medical Virology · 2021 · 11 citations