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GlossaryCD3 complex

group of proteins on T cells aiding immune response signaling

The CD3 complex is a group of proteins found on the surface of T cells, which are a type of white blood cell crucial for the immune system. These proteins work together to help the T cell recognize and respond to foreign invaders, such as viruses or bacteria, by transmitting signals from the cell surface to its interior, initiating an immune response.

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research Multiplex Matrix Network Analysis of Protein Complexes in the Human TCR Signalosome

32 citations , August 2016 in “Science Signaling”

Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.

research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases

22 citations , January 2012 in “Mediators of inflammation”

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

research Claudin Expression Modulations Reflect an Injury Response in the Murine Epidermis

9 citations , July 2007 in “Journal of Investigative Dermatology”

Claudin expression changes help the skin respond to injury.

research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus

3 citations , January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu”

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

research Bioinformatics Analysis of Genes Associated with Patchy-Type Alopecia Areata: CD2 May Be a New Therapeutic Target

4 citations , September 2019 in “Biomedical Papers/Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic”

CD2 might be a new treatment target for patchy alopecia areata.

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