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GlossaryTestosterone Levels (T levels)

measure of testosterone concentration in the bloodstream

Testosterone levels refer to the concentration of testosterone, a key male sex hormone, in the bloodstream. These levels can influence various bodily functions, including muscle mass, bone density, and hair growth. Abnormal testosterone levels, whether too high or too low, can lead to health issues such as alopecia, infertility, and mood disorders. Measurement of testosterone levels is often done through blood tests to diagnose and manage conditions related to hormonal imbalances.

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Exogenous Testosterone Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum Testosterone

research Exogenous Testosterone Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum Testosterone

506 citations, March 2005 in “The Journal of Clinical Endocrinology and Metabolism”

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

research Hyperandrogenemia in Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Association with Body Mass Index

19 citations, January 2017 in “Hormone Molecular Biology and Clinical Investigation”

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

research Elevated Serum Androstenedione Is Associated With a More Severe Phenotype in Women With Polycystic Ovary Syndrome

28 citations, April 2014 in “Hormones”

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

Serum Androgens and Prostate-Specific Antigen Levels in Androgenetic Alopecia: Is There a Difference Between Frontal and Vertex Baldness?

research Serum Androgens and Prostate-Specific Antigen Levels in Androgenetic Alopecia: Is There a Difference Between Frontal and Vertex Baldness?

1 citations, December 2017 in “Journal of The European Academy of Dermatology and Venereology”

Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.

research Treatment of Androgenetic Alopecia by Exosomes Secreted From Hair Papilla Cells and the Intervention Effect of LTF

August 2023 in “Journal of Cosmetic Dermatology”

Exosomes from hair papilla cells and the Chinese medicine Liao Tuo Fang can potentially promote hair growth and could be used to develop hair growth drugs.

research Effects of Long-Term Treatment With Finasteride (MK-906), a 5-Alpha Reductase Inhibitor, on Circulating LH, FSH, Prolactin, and Estradiol

10 citations, October 1992 in “Hormone and Metabolic Research”

Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.

research Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men

30 citations, August 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride doesn't affect hormone levels in normal men.

research Prevalence of Hyperandrogenemia in Polycystic Ovary Syndrome Diagnosed by the National Institutes of Health 1990 Criteria

118 citations, February 2009 in “Fertility and Sterility”

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Androgen Profiling by Liquid Chromatography–Tandem Mass Spectrometry in Healthy Normal-Weight Ovulatory and Anovulatory Late Adolescent and Young Women

research Androgen Profiling by Liquid Chromatography–Tandem Mass Spectrometry in Healthy Normal-Weight Ovulatory and Anovulatory Late Adolescent and Young Women

52 citations, June 2013 in “The Journal of Clinical Endocrinology and Metabolism”

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

research Can AMH Levels Distinguish LOCAH from PCOS Among Hirsute Women?

5 citations, April 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology”

AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.

research Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia

32 citations, January 1990 in “Clinical Endocrinology”

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone

28 citations, November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The normal human prostate does not significantly affect blood DHT levels.

research Oral Testosterone in Oil: Pharmacokinetic Effects of 5α-Reduction by Finasteride or Dutasteride and Food Intake in Men

22 citations, January 2006 in “International Journal of Andrology”

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

research Glutathione-S-Epoxide Transferase in Human Hair Follicles

4 citations, April 1986 in “Cancer Letters”

GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.

research Testosterone-Secreting Tumor or Insulin Resistance? Metformin as a Diagnostic and Therapeutic Trial

August 2013 in “Fertility and sterility”

Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.

research The Influence of Long-Term Treatment with Cyproterone Acetate or a Cyproterone Acetate-Ethinyl Estradiol Combination on Androgen Levels in Blood of Hirsute Women

14 citations, January 1980 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

Both treatments reduced androgen levels and hair growth in women with hirsutism.

Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration

research Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration

25 citations, April 2006 in “British Journal of Dermatology”

Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.

research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization

8 citations, April 2019 in “Journal of the Endocrine Society”

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness

research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness

59 citations, September 1994 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

research Serum C-19 Steroid Sulphates in Females with Clinical Hyperandrogenism

4 citations, January 1989 in “Journal of Steroid Biochemistry”

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

research Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

82 citations, February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

research Occult Ovarian Leydig Cell Tumor: When Laboratory Tells More Than Imaging

5 citations, October 2013 in “Endocrine”

Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance

2 citations, August 2021 in “Experimental and Therapeutic Medicine”

Moxibustion may help improve ovarian function by changing androgen levels.

Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

20 citations, June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery”

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

research Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness Between Korean and Caucasian Populations

10 citations, November 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

Nanomilled Oral Testosterone Plus Dutasteride Effectively Normalizes Serum Testosterone in Normal Men With Induced Hypogonadism

research Nanomilled Oral Testosterone Plus Dutasteride Effectively Normalizes Serum Testosterone in Normal Men With Induced Hypogonadism

10 citations, February 2008 in “International Journal of Andrology”

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

C19 and C21 5β/5α Metabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency

research C19 and C21 5β/5α Metabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency

55 citations, March 1990 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

The Differences Between Aromatizable And Non-Aromatizable Androgens In Relation To Body Composition And Metabolic Syndrome Risk Factors In Men

research The Differences Between Aromatizable And Non-Aromatizable Androgens In Relation To Body Composition And Metabolic Syndrome Risk Factors In Men

8 citations, March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology”

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

research Insights From Liquid Chromatography-Mass Spectrometry-Measured Androgens in Indian Women With Polycystic Ovary Syndrome

January 2024 in “Curēus”

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

research Development of Prostate Cancer in a Patient with Primary Hypogonadism: Intratumoral Steroidogenesis in Prostate Cancer Tissues

10 citations, October 2012 in “Andrology”

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.