Occult Ovarian Leydig Cell Tumor: When Laboratory Tells More Than Imaging

    October 2013 in “ Endocrine ”
    Rosa Maria Paragliola, Francesco Torino, Paola Senes … Salvatore Maria Corsello
    Studysummary This case report describes three instances where occult ovarian Leydig cell tumors were suspected based on severe hyperandrogenism symptoms, despite negative imaging findings, highlighting that elevated testosterone levels are a crucial diagnostic marker.
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    Research cited in this study 5

    1. How Should Postmenopausal Androgen Excess Be Evaluated? Clinical Endocrinology · 2011
    2. European Consensus on the Evaluation of Women Presenting with Excessive Hair Growth European journal of dermatology/EJD. European journal of dermatology · 2009
    3. Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred Because of Clinical Hyperandrogenism The Journal of Clinical Endocrinology and Metabolism · 2006
    4. Hirsutism New England journal of medicine/˜The œNew England journal of medicine · 2005
    5. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004

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    1. Occult Ovarian Leydig Cell Tumor: When Laboratory Tells More Than Imaging Endocrine · 2013