Occult Ovarian Leydig Cell Tumor: When Laboratory Tells More Than Imaging

October 2013 in “ Endocrine ”

Rosa Maria Paragliola, Francesco Torino, Paola Senes, Laura Castellino, Vanda Salutari, Alfredo Pontecorvi, Giovanni Scambia, Salvatore Maria Corsello

hyperandrogenism serum total testosterone Leydig cell tumors hirsutism virilization androgen levels bilateral ovariectomy histological analysis ovarian malignancy high testosterone hair growth male characteristics ovary removal tissue analysis ovarian cancer

Studysummary This case report describes three instances where occult ovarian Leydig cell tumors were suspected based on severe hyperandrogenism symptoms, despite negative imaging findings, highlighting that elevated testosterone levels are a crucial diagnostic marker.

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