35 citations
,
July 2015 in “Journal of Affective Disorders” This study found that women with polycystic ovary syndrome have significantly higher scores for affective temperaments and anxiety and depression than healthy controls, suggesting risk for depressive and anxiety disorders.
35 citations
,
December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
34 citations
,
May 2017 in “Lasers in Surgery and Medicine” This study found that combining low-level light therapy with topical minoxidil 5% may lead to better hair regrowth and patient satisfaction in treating female pattern hair loss compared to using each treatment alone.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” This review suggested that low-level light therapy using red/near-infrared light could be a safe and effective treatment for various skin and hair conditions, though more robust trials are needed to solidify its clinical utility.
33 citations
,
January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.
31 citations
,
June 2018 in “Dermatologic Surgery” In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.
31 citations
,
March 2018 in “Frontiers in Immunology” This article reviews the complexities and challenges in classifying systemic lupus erythematosus and the problematic role of the anti-dsDNA antibody as a biomarker, without presenting new experimental findings.
30 citations
,
October 2013 in “Lupus” This study identified distinct clinical and dermatoscopic features to differentiate non-scarring patchy alopecia in SLE from alopecia areata, emphasizing the value of serological tests in diagnosis.
29 citations
,
January 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that trichoscopic examination is useful for diagnosing and monitoring systemic lupus erythematosus, with severe diffuse non-scarring alopecia indicating active disease.
26 citations
,
March 2015 in “American journal of clinical dermatology” This study found that systemic mycophenolate mofetil and topical clobetasol were equally effective at reducing lichen planopilaris activity over six months, but satisfaction differed between the treatments.
18 citations
,
October 2018 in “Journal of The American Academy of Dermatology” This review indicates that many former FDA category D and X systemic dermatologic medications may negatively impact male fertility, with further research needed to assess potential teratogenic effects.
18 citations
,
May 2016 in “Annals of Medicine” This paper reviews seven major systemic causes of hair loss and provides a clinical evaluation framework but reports no new experimental results.
18 citations
,
October 2005 in “International Journal of Pharmaceutics” This study found that incorporating 0.5% TPGS into topical minoxidil solutions enhanced hair growth in mice, although increasing TPGS to 2% decreased effectiveness.
18 citations
,
January 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” This study reports that sequential high- and low-dose prednisolone therapy effectively promotes complete hair regrowth in 62% of children with severe alopecia areata, while minimizing severe side effects.
16 citations
,
December 2017 in “Journal of The American Academy of Dermatology” This study found that low-level laser therapy may reduce inflammation and increase hair thickness in patients with lichen planopilaris after six months of treatment, though the small sample size limits the findings.
16 citations
,
May 2011 in “Dermatologic therapy” This article reviews side effects and relapse rates of various systemic treatments for severe alopecia areata, reporting no new clinical findings.
14 citations
,
January 2020 in “Advances in Dermatology and Allergology” This study found that elevated serum levels of IL-15 in active alopecia areata patients are correlated with disease severity, suggesting it plays a role in disease pathogenesis.
13 citations
,
April 2020 in “Dermatology and therapy” This systematic review assessed cyclosporine's effectiveness with or without corticosteroids for treating alopecia areata, finding combined therapy more effective and with a lower recurrence rate than monotherapy, especially for severe cases, though results varied by alopecia type.
12 citations
,
April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” This review discusses the prenatal care guidelines for women with systemic lupus erythematosus and emphasizes the need for disease activity control to reduce maternal and fetal complications; it reports no new results.
11 citations
,
June 2015 in “Scientific Reports” In this study of Han Chinese women, the mitochondrial DNA N haplogroup was associated with a higher risk of late-onset systemic lupus erythematosus and its specific manifestations, such as skin impairment and neurological disturbances.
9 citations
,
January 2013 This study found that serum levels of zinc, copper, and selenium were significantly lower in patients with alopecia areata compared to healthy controls, regardless of the number of hair loss patches.
8 citations
,
April 2019 in “Journal of the Endocrine Society” In this study, long-term normalization of testosterone levels in postmenopausal women with hyperandrogenism did not improve body mass index, glucose, or lipid metabolism.
7 citations
,
March 2020 in “Lasers in Medical Science” LLLT is a safe, promising hair loss treatment, but more research needed.
7 citations
,
July 2019 in “Clinics in Dermatology” This review discusses various systemic diseases associated with secondary alopecia and reports no new clinical findings; it emphasizes the importance of addressing underlying conditions and using diagnostic tools like trichoscopy and histopathology.
6 citations
,
August 2020 in “Dermatology and Therapy” This study found that patients with alopecia areata had significantly lower serum vitamin D levels and higher odds of vitamin D deficiency, but no significant difference in serum calcium levels, compared to controls.
5 citations
,
May 2021 in “Veterinary medicine and science” In this study, cosyntropin-induced cortisol spikes did not affect hair cortisol concentration in captive grizzly bears, contrasting with stress responses observed in free-ranging bears during capture.
5 citations
,
November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
5 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.
3 citations
,
October 2019 in “JAAD Case Reports” This review discusses different forms and patterns of alopecia associated with lupus erythematosus and reports no new clinical results; the authors highlight distinct features of these conditions.
3 citations
,
March 2022 in “Korean Journal of Family Medicine” This case report highlights the challenge of diagnosing systemic lupus erythematosus in males and antinuclear antibody-negative patients, emphasizing the need for primary care doctors to maintain a high suspicion of the condition.