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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The Rotterdam Study aims to understand various diseases in older adults.

PGD2 stops hair growth and is higher in bald men with AGA.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Lowering testosterone speeds up wound healing in male mice.

The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.