November 2024 in “Journal of Translational Internal Medicine” This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.
March 2024 in “Tropical Journal of Natural Product Research” This study surveyed the use and potential toxicity of medicinal plants in the Fez-Meknes region of Morocco, documenting 59 toxic species used primarily for cosmetic purposes and minor illnesses, and identified hair loss and rheumatism as having the highest informant agreement ratios.
December 2023 in “Frontiers in endocrinology” This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.
This study found that all examined biomarkers and clinical features were elevated in systemic lupus erythematosus patients, particularly ANA and Anti-dsDNA autoantibodies, but no single biomarker was sensitive or specific enough for diagnosis.
September 2021 in “Meditsinskiy sovet = Medical Council” This study found that injecting blood plasma enriched with platelet growth factors significantly improved the healing and auditory function in patients with acute post-traumatic tympanic membrane perforation compared to natural regeneration.
January 2020 in “JoLS Journal of Life Sciences” This study found that a mixture of Red-BCQ and Agnex extract promoted greater hair growth and antioxidant effects in C57BL/6 mice compared to other groups, including minoxidil treatment.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
January 2018 in “Trace Elements in Medicine (Moscow)” Children with autism have different levels of certain metals and elements in their hair and blood, affecting symptoms.
January 2012 in “Durham e-Theses (Durham University)” This study found that knock-down of keratin 15 in various cell lines affected cell spreading, morphology, migration, differentiation, and proliferation, suggesting its role in maintaining the stem cell nature of keratinocytes.
July 2002 in “Australasian Journal of Dermatology” Maintaining anticoagulation is crucial for patients with antiphospholipid syndrome.
July 2002 in “Australasian Journal of Dermatology” This announcement in the Australasian Journal of Dermatology provides no new research findings or study results.
This study found that using SH-SY5Y cell lysate in Western blot analysis may improve the diagnosis of Satoyoshi syndrome by providing more consistent and clear immunoreactive band patterns compared to brain homogenate, potentially leading to earlier diagnosis and treatment.
18 citations
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February 2006 in “Brain & development” This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.
July 2022 in “medRxiv (Cold Spring Harbor Laboratory)” This review supports an autoimmune hypothesis for Satoyoshi syndrome, noting associations with autoantibodies and autoimmune diseases, and reports an observed improvement in most patients with corticosteroid or immunosuppressant treatments.
January 2017 in “대한본초학회지(본초분과학회지)” This study found that Sinseon-yukza-hwan extract has strong antioxidative properties, effectively inhibiting free radical generation, which supports its potential use as a natural antioxidant.
13 citations
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October 2003 in “Clinical pediatrics” In this case report, a 14-year-old boy with Satoyoshi syndrome did not improve with intravenous immunoglobulin but responded dramatically to steroid treatment.
2 citations
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June 2025 in “Medicina” This retrospective study in pediatric patients with Sjögren's syndrome found consistent indications of tear film instability and identified systemic features like arthralgia, Raynaud's phenomenon, and frequent autoantibody positivity, underscoring the value of integrating clinical and ophthalmological assessments for early diagnosis.
January 1995 in “Seoul National University Open Repository (Seoul National University)” This study found that skin sulfhydryl oxidase plays a role in keratinization and may contribute to skin's protective functions, with its expression influenced by irritants and differentiation modifiers.
1 citations
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January 1999 in “Dermatology”
July 2023 in “Journal of exploratory research in pharmacology” In this case report, a 47-year-old man with extensive psoriasis saw significant improvement in scaling and itching after using a new lotion containing clobetasol and other ingredients for one week, but further research is needed to confirm these findings.
This case report describes how unique endoscopic findings led to the diagnosis of Satoyoshi syndrome coexisting with systemic lupus erythematosus and gastric adenoma, expanding the endoscopic understanding of the syndrome.
17 citations
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April 2013 in “Experimental and Therapeutic Medicine” This study found that anti-Sjögren's syndrome type B antibodies are highly specific for diagnosing systemic lupus erythematosus and are associated with several clinical symptoms, including cheek erythema and alopecia.
2 citations
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August 2019 in “International Journal of Applied Pharmaceutics” This study explored the use of SOD-loaded niosomes as carriers to enhance the delivery of superoxide dismutase into hair follicles on guinea pig skin, finding that niosomes improved SOD penetration and preservation compared to free SOD, suggesting their potential as effective delivery vehicles.
55 citations
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November 2018 in “American journal of human genetics” This study identified five mutations in the gene LSS in individuals with unexplained hypotrichosis simplex, highlighting a potential role of mislocalized LSS proteins in disrupting hair follicle biology.
January 2011 in “Web journal anti-aging medicine/Anti-aging medicine” In this study, kamishoyosangoshimotsuto extract improved skin moisture, texture, and brightness, as well as hair thickness and strength in women with skin and scalp hair problems over 24 weeks.
16 citations
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June 1992 in “PubMed” In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.
2 citations
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November 2006 in “APLAR Journal of Rheumatology” This article narrates the author's personal journey with systemic lupus erythematosus over 15 years, highlighting the challenges and strategies for managing this complex disease and maintaining quality of life.
10 citations
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August 2021 in “Cosmetics” This study identified an optimal sulfate-free and silicone-free conditioning shampoo formulation using 1% hyaluronic acid at 800 kDa, 10% acidic sophorolipid, and 1% sodium chloride, which maintains essential conditioning and cleansing properties without compromising on performance.
1 citations
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October 2015 in “추계총회 및 학술대회” The extract promotes hair growth and may help treat hair loss.
8 citations
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June 2019 in “Orphanet journal of rare diseases” This review of 64 published cases of Satoyoshi syndrome from 1967 to 2018 reports that corticosteroids were the most widely used and effective treatment, improving symptoms in most cases, while muscle relaxants like dantrolene primarily benefited muscle symptoms without affecting other symptoms.