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This study found that during amelogenesis in Msx2 null mice, a dysfunctional enamel organ developed due to abnormal epithelial transformation and lacked proper enamel formation.

This review examines the histochemistry and keratinization processes of human hair, exploring the structural roles of keratin proteins, protein chains, and lipids, but offers no new results.

This study found that the stratum corneum of scalp skin in humans has distinct functional characteristics compared to the facial skin and volar forearm, including higher hydration levels and intermediate epidermal turnover rates.

This study's simulations revealed the complex "onion-like" organization of a lipid nanoemulsion droplet containing vitamins A and E for skin delivery, showing distinct concentration patterns of these vitamins within different layers of the nanodroplet.

This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.

In this study, researchers discussed how specific protein interactions in reptile skin allow for the development of protective structures like scales and scutes, which facilitated reptiles' adaptation to terrestrial environments.

This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.

This study found that trichohyalin, a protein previously thought to be restricted to hair and tongue, is also present in isolated cells within the granular layer and stratum corneum of normal human epidermis.

This study found that keratin filament networks in SG1 cells of mice undergo dynamic changes during cornification, impacting the barrier function of the stratum corneum.

Keratins are crucial for cell structure, growth, and disease risk.

This study demonstrated that RNA-seq can effectively expand hair follicle transcriptomic profiling in a multi-center study, offering deeper insights than blood transcriptomics alone.

This study found that trichohyalin is expressed in various normal and pathological epithelia beyond hair follicle cells, where it is uniquely associated with filaggrin, suggesting a specific role in aggregating K6/K16-containing intermediate filaments.

This study developed a model showing that keratin elasticity in skin may be influenced by electrostatic and bridging interactions between keratin filaments, contingent on the balance of charges in the surrounding medium.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

This study suggests that fish oil, specifically its components EPA and DHA, play a beneficial role in promoting skin health by supporting epidermal growth and reducing proinflammatory cytokines.

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.

Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.

This study found that hair follicles contribute significantly to caffeine absorption shortly after topical application, with a faster absorption rate compared to the stratum corneum.

This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.

This study suggests that age-related changes in skin elasticity reduce its stability against wrinkling, and anti-aging strategies should focus on addressing elastic mismatches between skin layers.

This study suggests that adjusting the ratios of keratin-associated proteins to keratin intermediate filaments can create keratin/chitosan hydrogels with more consistent gel properties for tissue engineering.

This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.

This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.

This study found that terbinafine prevented the invasion of keratin by Trichophyton mentagrophytes in experimental models replicating human dermatomycoses.

This review outlines the histological structures of the skin, highlighting species and regional differences in dermal absorption and obstacles encountered in toxicological assessments due to epidermal thickness variability, contact dermatitis reactions, and stem cell vulnerabilities.

This article reviews dermatological research on black skin, emphasizing its unique physiological characteristics and common conditions like acne and eczema, and suggests more focus is needed on its structural differences and clinical responses.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

This study found that combining lecithin reverse wormlike micelles with isopropyl myristate enhanced the skin permeability of a model hydrophilic drug, facilitated by interactions with sebum in hair follicles.