Unconventional Protein Secretion of Keratin 75 by Ameloblasts In Vivo

    April 2018 in “ D-Scholarship@Pitt (University of Pittsburgh) ”
    Xu Yang
    Studysummary This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on d-scholarship.pitt.edu →
    Discuss this study in the Community →

    Research cited in this study 7

    1. Pseudofolliculitis Cutis: A Vexing Disorder of Hair Growth British journal of dermatology/British journal of dermatology, Supplement · 2014
    2. Cytokeratin 15 Expression in Central, Centrifugal, Cicatricial Alopecia: New Observations in Normal and Diseased Hair Follicles Journal of Cutaneous Pathology · 2011
    3. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    4. Mice Expressing a Mutant KRT75 (K6hf) Allele Develop Hair and Nail Defects Resembling Pachyonychia Congenita Journal of Investigative Dermatology · 2007
    5. An Unusual Ala12Thr Polymorphism in the 1A Alpha-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae Journal of Investigative Dermatology · 2004
    6. Discovery of a Novel Murine Keratin 6 (K6) Isoform Explains the Absence of Hair and Nail Defects in Mice Deficient for K6a and K6b The Journal of Cell Biology · 2001
    7. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998