Co-Option of Hair Follicle Keratins into Amelogenesis Is Associated with the Evolution of Prismatic Enamel: A Hypothesis

    October 2017 in “ Frontiers in Physiology ”
    Elia Beniash
    Studysummary This article proposes a hypothesis that KRT75, a protein found in hair follicles, was evolutionarily co-opted by ameloblasts during the development of prismatic enamel in synapsids, but reports no new results.
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    Research cited in this study 7

    1. Pseudofolliculitis Cutis: A Vexing Disorder of Hair Growth British journal of dermatology/British journal of dermatology, Supplement · 2014
    2. Increased Rate of Hair Keratin Gene Loss in the Cetacean Lineage BMC Genomics · 2014
    3. Early Inductive Events in Ectodermal Appendage Morphogenesis Seminars in cell & developmental biology · 2014
    4. Recurrent Functional Divergence of Early Tetrapod Keratins in Amphibian Toe Pads and Mammalian Hair Biology Letters · 2013
    5. The Chicken Frizzle Feather Is Due to an Alpha-Keratin (KRT75) Mutation That Causes a Defective Rachis PLoS Genetics · 2012
    6. Identification of Reptilian Genes Encoding Hair Keratin-Like Proteins Suggests a New Scenario for the Evolutionary Origin of Hair Proceedings of the National Academy of Sciences · 2008
    7. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998

    Related research 2

    1. Msx2 Prevents Stratified Squamous Epithelium Formation in the Enamel Organ Journal of Dental Research · 2018
    2. Co-Option of Hair Follicle Keratins into Amelogenesis Is Associated with the Evolution of Prismatic Enamel: A Hypothesis Frontiers in Physiology · 2017