Expression of Keratin 75 (K6hf) in Oral Squamous Cell Carcinoma

    January 2011 in “ Dental Medicine Research ”
    Shizunari Obara, Gou Yamamoto, Shigeo Hayashi … Tetsuhiko Tachikawa
    Studysummary This study suggests that Keratin 6hf may be a potential marker of oral squamous cell carcinoma and could play a role in its progression, though further research is needed to understand its function.
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    Research cited in this study 8

    1. Mice Expressing a Mutant KRT75 (K6hf) Allele Develop Hair and Nail Defects Resembling Pachyonychia Congenita Journal of Investigative Dermatology · 2007
    2. Cylindroma as a Tumor of Hair Follicle Origin Journal of Investigative Dermatology · 2006
    3. Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles Journal of Investigative Dermatology · 2003
    4. A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2002
    5. Discovery of a Novel Murine Keratin 6 (K6) Isoform Explains the Absence of Hair and Nail Defects in Mice Deficient for K6a and K6b The Journal of Cell Biology · 2001
    6. Delayed Wound Healing in Keratin 6a Knockout Mice Molecular and Cellular Biology · 2000
    7. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    8. Hair Follicle Companion Layer: Reacquainting an Old Friend ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1995