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Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Both drugs lower DHT levels, with GI198745 being more effective.

Spironolactone can reduce hair growth in women with hirsutism.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Genetics and hormones cause hair loss; finasteride treats it safely.

SHBG may be a useful early indicator and treatment target for PCOS.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Finasteride helps reduce heart issues and improves heart function.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

HIV can cause unusual and severe skin problems that are hard to treat.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.