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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

A new compound effectively inhibits human 5α-reductase 1.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

RE-ORGA, a Korean herb extract, may help prevent hair loss.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

DHT affects testicular development and regulates spermatogenesis in some fish.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Compounds from the plant Mammea siamensis may help treat hair loss.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

DA-5512 effectively improves hair growth and health, performing better than minoxidil.

Menthol boosts the hair growth effects of Phyllanthus niruri gel.

Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.