The Influence of Menthol in Ethanol Extract of Phyllanthus Niruri Gel as a Hair Growth Promoter in Male Wistar Rats

The study investigated the potential of menthol in enhancing the hair growth-promoting effects of Phyllanthus niruri ethanol extract gel in male Wistar rats. Four groups were tested: a normal group, a negative control, an E1 group (5% P. niruri extract gel without menthol), and an E2 group (5% P. niruri extract gel with menthol). Results showed that the E2 group had significantly greater hair length (12.45±3.457 mm) and hair weight (28.53±7.681 mg) compared to the E1 group (10.67±2.455 mm and 19.87±9.552 mg). The study concluded that menthol enhances the hair growth and thickness effects of P. niruri ethanol extract gel.