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Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Effective PCOS treatments require targeting specific signaling pathways.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Finasteride and minoxidil together work best for male hair loss.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Androgenetic alopecia in women needs more research and better management strategies.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Combination therapy improves hair growth in advanced hair loss.

Men with male pattern baldness don't necessarily have high levels of Dehydroepyandrosterone-sulfate, and there's no link between its levels and the severity of hair loss.

More research is needed to understand how testosterone is maintained in adult males.

Compound 15a was effective in inhibiting 5α-reductase.

Certain chemicals and peptides can promote hair growth or prevent baldness.

Minoxidil and finasteride are effective for male hair loss; minoxidil also helps female hair loss, with some treatments needing more research.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Finasteride doesn't harm bone density in older men with BPH.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.