Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that glycyrrhizic acid significantly reduced stem cell characteristics of dermal papilla cells by down-regulating key signaling pathways, suggesting potential use in suppressing unwanted hair growth.

This study suggests that short-term treatments with specific small molecules may enhance the differentiation potential and stem cell properties of human amniotic fluid stem cells.

This study found that in neonatal mice, the absence of the NG2 proteoglycan leads to reduced epidermal thickness and delayed subcutis thickening due to impaired proliferation and adipocyte deficiencies.

In this study, researchers found that while both hair follicles and skin dermis-derived neural crest stem cells are suitable for large-scale manufacturing, skin dermis cells grow faster and are easier to obtain.

This study examined the effects of WNT10B on dermal papilla cells in vitro, finding that it alters gene expression, decreases protein synthesis, and upregulates a specific signaling pathway, potentially influencing hair follicle morphogenesis.

In this study, researchers observed that low levels of fucose-binding lectin staining characterize limbal epithelial progenitor cells, which maintain a high proliferative capacity and may be enhanced by inhibiting fucosylation, offering insights for regenerative therapy of the limbal stem cell niche.

In this study, the researchers reported that Krox20 plays a crucial role in epidermal homeostasis and hair development, influencing stem cell maintenance and cell survival through the modulation of cellular pathways.

This review discusses strategies for identifying and characterizing adult stem cells in mice and highlights their potential and limitations, but reports no new experimental results.

The study found that aging in hair follicle stem cells leads to hair follicle miniaturization and eventual hair loss in both wild-type mice and humans by proteolyzing type XVII collagen.

This bibliometric analysis identified SGK1 as a key factor in cancer, showing that its dysregulation can lead to tumor growth and treatment resistance. The authors highlighted SGK1's potential as a therapeutic target, but note that further research is needed to develop effective treatment strategies.

In this study on mice, elevated IGF-1 levels in the skin were linked to premature aging of hair follicles, but interventions like reducing IGF-1 or using senolytic treatments helped restore stem cell health and counteract aging effects.

This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.

This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.

This study found that extracellular vesicles derived from hair follicle mesenchymal stromal cells demonstrated similar potential to those from adipose tissue in promoting cell proliferation and migration, enhancing angiogenesis, and protecting cells under stress, suggesting promise for chronic wound treatment.

This review summarizes existing reports on placenta extract for treating liver injury and discusses its mechanisms but provides no new clinical results.

This study developed an efficient method for isolating and enriching multipotent ovine hair follicle stem cells, which may aid in research on the ovine hair cycle and future wool production.

This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

This study found that the overexpression of the lncRNA HOTTIP in glioma cells increased resistance to the chemotherapy drug temozolomide, suggesting a key role for miR-10b and EMT processes in this resistance.

This study shows that NIPP1 deficiency in mouse epidermis leads to hyperproliferation, hair loss, and chronic skin inflammation, which can be partially alleviated by dexamethasone treatment.

In this discussion, the authors highlight the murine cornea as a powerful model for stem cell research, revealing new insights into stem cell properties, differentiation flexibility, and the importance of the stem cell niche, with potential implications for understanding various tissues, diseases, and therapies.

This study found that scoparone increased the expression of certain pluripotency-related proteins in dermal papilla cells, suggesting a potential new mechanism for enhancing hair growth.

This review discusses the role of hair follicle stem cell metabolism, ageing, and microenvironment in hair growth disorders and compiles recent research on using stem cell-based regenerative medicine for treating alopecia, without reporting new clinical results.

This study suggests that the CXCL8 gene may regulate cashmere fineness in Liaoning cashmere goats, providing new insights into the cellular mechanisms of cashmere growth and quality.

This study reports that human adipose-derived stem cells cultured with platelet lysate instead of fetal bovine serum demonstrate enhanced stress resistance, reduced cellular aging, and faster wound healing in mice, due in part to upregulated stress response and proliferation genes.

This study found that mesenchymal stem cells from chronically inflamed human livers maintain their key cellular characteristics, supporting their potential use in developing liver cell therapies.

This study found that a quinazoline derivative, SH-340, increased skin barrier-associated factors and inhibited TSLP expression and STAT6 phosphorylation in human primary keratinocytes, suggesting potential benefits for alleviating inflammation and improving skin barrier function in atopic dermatitis.

This study found that a large number of pelage hair follicle mesenchymal stem cells can be efficiently isolated using two-step Ficoll Density Gradient Sedimentation, promoting hair growth by secreting exosomes in mice.

This review summarizes recent insights into corneal limbal stem cell differentiation and the potential role of progenitor-like cells, but reports no new experimental results.

Retinoic acids temporarily change skin stem cells to a slower cycle and more differentiated state.

This study found that 808 nm laser photobiomodulation altered mitochondrial respiration and enhanced osteogenic protein expression in human dental pulp stem cells, with the effects being dose-specific and more pronounced at 15 J/cm².