Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this comprehensive review, researchers examine the p63 gene's crucial role in skin development and pathology, highlighting its regulation of cell processes and its potential therapeutic implications for disorders like ectodermal dysplasia.

This study reports that the novel small molecule IM176OUT05, by modifying stem cell metabolism, promoted hair regrowth and increased hair follicle numbers in mice.

This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.

This review discusses recent advancements in the study and application of epidermal stem cells for wound healing and tissue engineering, without presenting new experimental findings.

This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

This article discusses the hair follicle's regenerative cycles and the molecular mechanisms influencing them, emphasizing the need for therapeutic targeting of the "hair cycle clock" to manage hair growth disorders, without reporting new research findings.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

This review introduces the morphological and molecular principles of hair follicle development but reports no new experimental results, focusing on recent insights and forming a working hypothesis.

This essay discusses the establishment, maintenance, and role of skin stem cells in tissue homeostasis, wound repair, and their relation to skin cancer, without reporting new experimental findings.

This review discusses the role of PPARs in skin health, suggesting both potential benefits and adverse effects, but reports no new experimental results; the authors emphasize the need for more research to understand these pathways.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.

This review discusses the potential applications and challenges of small molecules in regenerative medicine, but it reports no new research findings.

This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.

This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.

Krox20 is important for cell differentiation in the brain and hair follicles.

This review discusses the potential of exosomes and the secretome in stem cell-based regenerative therapies but reports no new experimental findings.

This review discusses recent advances in how proinflammatory cytokines affect epidermal stem cell function during skin wound healing and introduces potential therapies targeting these cells and cytokines.

This study observed that fibrosis occurs in the bulge region of hair follicles affected by androgenetic alopecia and is correlated with the hair miniaturization process.

This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.

This study found that GDNF promotes hair formation and skin wound repair by enhancing the self-renewal and differentiation of bulge stem cells in mice.

This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.

This study developed a novel zinc-releasing hydrogel, Zn-Gel, which promoted wound healing by controlling zinc ion release and demonstrated excellent compatibility and efficacy in enhancing cell proliferation, blood vessel formation, and tissue regeneration in vitro and in vivo settings.

This review outlines the processes and potential of stem cells in regenerating skin, hair, and other tissues but presents no new experimental findings.

This review discusses different processing methods for isolating human AD-SVFs/AD-MSCs using various kits and reports no new clinical results, highlighting the need for standardized preparation techniques.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

This study shows that alpha 6 + /MHCI - cells have gene expression profiles similar to hair follicle stem cells, suggesting they may be enriched for stem cells.