Exosomes for Regeneration, Rejuvenation, and Repair

    January 2018 in “ Stem cells in clinical applications ”
    Joydeep Basu, John W. Ludlow
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    TLDR Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
    The document from January 1, 2018, explores the use of exosomes in regenerative medicine, highlighting their potential in tissue repair, wound healing, and as a noncytotoxic alternative to live cell therapies. Exosomes, which are extracellular vesicles, have been shown to carry regenerative properties, mediating effects such as inhibiting apoptosis, stimulating angiogenesis, and modulating inflammation. Studies cited include the use of mesenchymal stem cell-derived exosomes in accelerating wound healing and promoting hair growth, as well as cardiosphere-derived cell exosomes improving cardiac function in rat models. The document also addresses the challenges of large-scale production and the development of synthetic exosome mimetics. It notes the potential of exosomes as biomarkers and their advantages over cell-based therapies in terms of manufacturing and storage. Regulatory and intellectual property issues are also discussed, along with the need for further clinical trials and research into the mechanisms of exosome-mediated regeneration.
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      community Has anyone tried Exosomes from Musely or somewhere else?

      in Hair Systems  3 upvotes 3 weeks ago
      Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community How Does Exosome Therapy Work for Hair Loss?

      in Research/Science  5 upvotes 1 year ago
      Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

      community How is no one talking about this?

      in Treatment  6 upvotes 3 months ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.

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