TLDR Injecting young pig stem cells can make old pig skin look younger and more elastic.
The study explored the rejuvenation of aged pig skin by transplanting granulocyte colony-stimulating factor-induced peripheral blood stem cells from a young pig. The treatment resulted in increased collagen, elastin, hyaluronic acid, and CD44, leading to tighter and more elastic skin, and enhanced epidermal cell renewal. The stem cells primarily localized in hair follicles, suggesting their role in skin rejuvenation. While the study showed promising results in modifying the microenvironment of aged skin and promoting regeneration, it was limited by a small number of animals and a short time frame, indicating the need for further research.
59 citations
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,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
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,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” The secretome from mesenchymal stem cells shows promise for treating skin conditions and improving skin and hair health, but more research is needed.
