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    Did you mean Stem Cell Function?
    Glossary Stem Cell Function

    ability to self-renew and become specialized cell types

    Stem cell function refers to the ability of stem cells to self-renew and differentiate into various specialized cell types. This means they can both replicate themselves to maintain the stem cell pool and transform into different types of cells needed for growth, repair, and maintenance of tissues, including hair follicles. This dual capability is crucial for regenerative medicine and understanding conditions like alopecia, where hair growth is disrupted.

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    1. Biomimetic cell-adhesive ligand-functionalized peptide composite hydrogels maintain stemness of human amniotic mesenchymal stem cells Regenerative Biomaterials · 2021 · 14 citations
    2. Pluripotent Hair Follicle Neural Crest Stem-Cell-Derived Neurons and Schwann Cells Functionally Repair Sciatic Nerves in Rats Molecular Neurobiology · 2009 · 36 citations
    3. Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation Stem cells · 2017 · 13 citations
    4. New substrates for stem cell control Philosophical Transactions of the Royal Society B · 2018 · 11 citations
    5. The Hair Follicle Bulge: A Niche for Adult Stem Cells Microscopy and Microanalysis · 2011 · 19 citations
    6. Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle British Journal of Dermatology · 2014 · 25 citations
    7. Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine Frontiers in Bioengineering and Biotechnology · 2023 · 2 citations
    8. Epidermal stem cell fate: what can we learn from embryonic stem cells? 2007 · 15 citations
    9. The hair follicle enigma Experimental Dermatology · 2017 · 25 citations
    10. 583 Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocytes 2022
    11. Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling Microsystems & Nanoengineering · 2026
    12. Keratinocyte Stem Cells: Role in Aging IntechOpen eBooks · 2022 · 1 citations
    13. Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles Interdisciplinary materials · 2025
    14. Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2023
    15. Cell death as an architect of adult skin stem cell niches Cell death and differentiation · 2024
    16. B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance Cell Reports · 2012 · 26 citations
    17. Functional stem-cell based tissue engineered vascular grafts for high-risk donor populations D-Scholarship@Pitt (University of Pittsburgh) · 2015
    18. The Role of Cell Polarity Regulator aPKC in Hair Follicle Stem Cell Maintenance and Wound Healing Nihon Ika Daigaku Igakkai Zasshi · 2020
    19. Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins Stem cells · 2010 · 106 citations
    20. Effects of storage culture media, temperature and duration on human adipose‑derived stem cell viability for clinical use Molecular Medicine Reports · 2019 · 19 citations
    21. 516 Functional annotation of genes underlying hair disorders 2017
    22. Modern strategies for the prevention and treatment of post-burn scars (a systematic review) Russian Journal of Transplantology and Artificial Organs · 2025
    23. Faculty Opinions recommendation of Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    24. Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes Heliyon · 2024 · 1 citations
    25. A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells Research Square (Research Square) · 2020
    26. Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures Biomaterials · 2016 · 36 citations
    27. Engineering the niche for hair regeneration — A critical review Nanomedicine: Nanotechnology, Biology and Medicine · 2018 · 27 citations
    28. Preservation of melanoblasts of white hair follicles of segmental vitiligo lesions: A preliminary study 2010 · 7 citations
    29. Comprehensive Review on Hair Loss and Restorative Techniques: Advances in Diagnostic, Artistry, and Surgical Innovation Cureus · 2025
    30. Tissue engineering; strategies, tissues, and biomaterials Biotechnology and Genetic Engineering Reviews · 2017 · 203 citations