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Blood vessels and specific genes help turn cartilage into bone when bones heal.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Baby teeth stem cells can potentially grow organs and treat diseases.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Galectin-1 helps in RNA processing in cell nuclei.

Certain transporters are found in human hair follicles and may affect hair growth and loss.

Scientists successfully created fully functional hair follicles using bioengineering methods and stem cells.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

White hair follicles in vitiligo have fewer and less functional melanocytes.

Researchers found that certain RNA sequences play a role in yak hair growth and these sequences are somewhat similar to those in cashmere goats.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Stem cell niches support, regulate, and coordinate stem cell functions.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.