Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in mouse skin, the activation of stem/progenitor cells is synchronized across different niches during growth, with the glutamate transporter SLC1A3 playing a crucial role in this process.

This review summarizes recent progress in human hair follicle bulge cell research, particularly the characterization and isolation of these stem cells, but reports no new experimental results.

This study found that isolated hair follicle outer root sheaths from mice can regenerate new dermal papillary structures in vitro, with stem cells and neutrophils playing key roles in the regeneration process.

This review discusses the generation of germ cell-like cells from skin-derived stem cells and reports no new results; the potential for these cells to produce viable progeny remains unclear.

This study found that the transcription factor p63 is crucial for horizontal basal cell differentiation in the olfactory epithelium, suggesting a p63-dependent mechanism activates reserve stem cells after injury.

In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.

This study found that in adult mouse skin, reduced levels of histone H3 K4/K9/K27me3 during hair follicle stem cell quiescence are linked to proper tissue homeostasis.

This article reviews the development and use of induced pluripotent stem cell models and artificial organoids for studying neurodevelopmental disorders, but it reports no new clinical findings.

This study shows that macrophage-induced TNF signaling can activate hair follicle stem cells and promote new hair follicle formation after wounding by regulating AKT/β-catenin pathways.

This review discusses the role of various genetic regulators in maintaining human mesenchymal stem cell stemness and highlights strategies for ex-vivo expansion, but reports no new clinical findings.

This review discusses the flexibility and diversity of tissue stem cell systems, particularly focusing on the motility and ligand distribution of spermatogenic stem cells, without presenting new experimental results.

This study revealed that Vav2 and Vav3 play roles in regulating hair follicle bulge stem cells in normal conditions and cancer stem cell activation and remodeling in mice.

This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.

This study found that platelet-derived growth factor signaling is crucial for maintaining the hair follicle dermal stem cell pool and supporting their regenerative capacity.

This study found that, despite a major depletion of SOX2-expressing stem cells in the pituitary, there was no effect on endocrine cell homeostasis or response to certain stressors in adult mice.

This study discovered that in *Drosophila*, knockdown of specific storage proteins in adipocytes decreased germline stem cell maintenance, implicating a role for these proteins in adult tissue regulation.

This study found that far-infrared radiation preconditioning significantly enhanced the proliferation, survival, and migration of bone marrow-derived stem cells in vitro, indicating potential therapeutic benefits for cardiac ischemia treatment.

This study found that constitutively active Stat3 in transgenic mice led to reduced keratinocyte stem cell populations in hair follicles, altering stem/progenitor cell dynamics and homeostasis.

In this study, researchers reported a case of severe chronic telogen effluvium in a COVID-19 patient who showed hair regrowth after five monthly treatments with stem cell serum, suggesting its potential as an adjunct or alternative to conventional therapies for COVID-19-induced hair loss.

This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.

This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.

This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.

This study reported that applying stem cell serum daily resulted in eyebrow hair regrowth in a patient with chronic secondary cicatricial alopecia, and prevented hair loss in another patient with acute eyebrow trauma, suggesting it as a noninvasive treatment alternative.

This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.

This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.

Plant extracts might help control stem cell growth for medical use.

This study found that PSAT1 is a key regulator of cellular survival and regenerative capacity in cashmere goat hair follicle stem cells, highlighting its role in the SHF cycle and its potential as a target to boost cashmere fiber production.

This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.

This study used a 3D live imaging system to map cell dynamics in human hair follicles, revealing patterns of cell movement and division that help explain hair fiber extrusion during hair growth.

This review summarizes the potential therapeutic applications of stem cells in dermatology, emphasizing their role in restorative and regenerative treatments through injections, topical applications, and scaffolds, supported by advancements in laboratory processes and quality control.