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Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

The chapter explains common scalp conditions, including infections, infestations, and tumors.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

New therapies are being developed that target integrin pathways to treat various diseases.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

TGM3 is important for skin and hair structure and may help diagnose cancer.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

Reflectance confocal microscopy is useful for diagnosing and monitoring skin diseases, but it has limitations and requires expertise for correct use.