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This study identified the Itpr3 gene as responsible for the tufted hair loss phenotype in the BTBR mouse strain.

This study concluded that specific SNPs in the TRPS1 gene significantly alter its protein structure, affecting interactions and contributing to the development of congenital hypertrichosis.

In this study, total Sry transcript expression in various rat tissues was linked to Acsl3 expression, suggesting that Sry may play a role in regulating fatty acid metabolism.

This study found that the Wnt10b gene promotes, while the SFRP2 gene inhibits, hair growth in Wanxi Angora rabbits, influencing the hair growth cycle and follicle regeneration.

This study found hair regrowth in the majority of AA-affected mice and rats treated with diphencyprone, suggesting its potential utility for understanding human alopecia areata and the drug's therapeutic action.

This review discusses the potential of polydeoxyribonucleotide (PDRN) for various dermatological treatments and highlights its significant effects on wound healing, anti-aging, acne scars, and hair loss, but emphasizes the need for further clinical studies.

This study found that Secretory Phospholipase A2-IIA (sPLA2-IIA) promotes proliferation through JNK/c-Jun signaling, distinctively affecting normal stem cells and cancer cells, suggesting it as a potential target for cancer treatment.

This study found that root hair growth is influenced by a complex interplay of auxin, inorganic phosphate, and transcription factors RSL2/RSL4, with reactive oxygen species playing a key role in this regulation.

This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.

In this study, auricular electrostimulation effectively relieved dextran-induced pruritus in mice, comparable to loratadine treatment, and is attributed to down-regulating the H1R/TRPV1 signaling pathway and reducing inflammatory cells in the skin.

This study suggests that a position effect disrupting TRPS1 expression may be linked to hypertrichosis in both Ambras syndrome in humans and a similar phenotype in Koa mice.

This article corrects a duplication error in a previous publication and reports no new research findings.

This study found that the small signaling peptide RALF22 plays a key role in root hair growth response to volatile compounds emitted by Penicillium aurantiogriseum through ethylene, auxin, and photosynthesis signaling in Arabidopsis.

In this study, researchers found that TSPyV T antigens can disrupt normal cell differentiation and proliferation in hair follicles and interfollicular epidermis, possibly contributing to trichodysplasia spinulosa pathology.

This study found that the desmosomal protein desmoplakin is crucial for proper epidermal morphogenesis and radial intercalation in developing Xenopus embryos, affecting keratin organization and ectodermal structures.

In this study, researchers observed that acute stress increased levels of the enzyme 5αR2 in the medial prefrontal cortex of male rats, affecting stress reactivity, but this effect was not seen in females.

This study identified ten novel compounds that may effectively target steroid 5 alpha-reductase 2 (5αR-2) for potential treatment of benign prostate hyperplasia, exhibiting comparable binding energies to existing drugs like finasteride and dutasteride.

This discussion reviews the shift in pharmaceutical strategy towards evidence-based and structure-guided drug development, highlighting ongoing challenges and efforts in computer-aided drug design without presenting new clinical results.

In this study, researchers found that overexpression of CRABP2 enhanced the proliferation of dermal papilla cells in Hu sheep through activation of the Wnt/β-catenin pathway, even when the pathway was inhibited.

In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.

In this study, researchers using QM/MM simulations identified key molecular motions and residue interactions in the enzyme SRD5A2 that significantly influence its catalytic efficiency, demonstrating that specific residues play critical roles in stabilizing transition states and reducing activation barriers.

This study found that cPPARγ and dnPPARγ isoforms are differentially expressed in healthy human skin, suggesting that PPARγ modulators may have compartment-specific effects depending on isoform presence.

This study found that RSPO1, a Wnt/β-catenin pathway agonist, significantly induces insulin-producing β cell replication and neogenesis in various settings, offering a promising potential therapy for diabetes.

In this study, researchers found that methylation of the SRD5A2 gene in blood and tissue samples can serve as a biomarker to predict men's clinical response to finasteride treatment for benign prostatic hyperplasia, offering a non-invasive method for assessing potential treatment success.

In this study, the researchers used the dual-flow-RootChip to show that Arabidopsis roots can locally adapt their hair development in response to asymmetric phosphate conditions.

This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.

This study introduced a high-viscosity epoxy photoresist to enhance the fabrication of complex microstructures with monolithic integration and mechanical stability, enabling advancements in two-photon 3D printing for creating functional micro-mechanical devices.

This study found that distinct spiny hair morphologies in rodents arose independently multiple times but did not link the Ecdysoplasin A receptor gene mutation that affects human hair to these variations.