RSPO1, A Potent Inducer of Pancreatic Beta Cell Neogenesis

    May 2025 in “ Cell Reports Medicine ”
    Serena Silvano, Tiziana Napolitano, Magali Plaisant … Patrick Collombat
    Studysummary This study found that RSPO1, a Wnt/β-catenin pathway agonist, significantly induces insulin-producing β cell replication and neogenesis in various settings, offering a promising potential therapy for diabetes.
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    Research cited in this study 2

    1. KY19382, A Novel Activator of Wnt/β-Catenin Signalling, Promotes Hair Regrowth and Hair Follicle Neogenesis British Journal of Pharmacology · 2021
    2. Targeting the Wnt Pathways for Therapies Molecular and cellular therapies · 2014