Sry Transcript Expression in Five Adult Male Rat Tissues and Correlation with Acsl3 Transcript Expression
December 2010
in “
OhioLink ETD Center (Ohio Library and Information Network)
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Studysummary In this study, total Sry transcript expression in various rat tissues was linked to Acsl3 expression, suggesting that Sry may play a role in regulating fatty acid metabolism.
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The study investigated the expression of the transcription factor Sry in five adult male rat tissues and its correlation with Acsl3 transcript expression. Sry was found to be expressed in the cerebral cortex, ventricle, atrium, aorta, and skeletal muscle of WKY, SHR/y, and SHR male rats, with significant differences in expression levels across tissues and strains. Notably, Sry expression in the cerebral cortex was significantly higher than in other tissues. The study also found that total Sry transcript expression correlated strongly with Acsl3 expression (R2=0.78), suggesting a potential regulatory role of Sry in fatty acid metabolism. These findings indicated differential functions of Sry loci and highlighted its possible involvement in metabolic processes.