The Early Region of Trichodysplasia Spinulosa Polyomavirus Drives Proliferation, Altered Differentiation, and Ectopic Expression of Hair Follicle Differentiation Markers in Interfollicular Tail Epidermis
trichodysplasia spinulosa TSPyV polyomavirus hair follicle disorder immunosuppressed viral early region genes dysmorphic hair follicles hyperplastic interfollicular tail epidermis epidermal keratins inner root sheath marker trichohyalin hair-specific keratin TS polyomavirus hair disorder immunosuppression ER genes abnormal hair follicles thickened skin skin keratins inner root sheath hair keratin
Studysummary In this study, researchers found that TSPyV T antigens can disrupt normal cell differentiation and proliferation in hair follicles and interfollicular epidermis, possibly contributing to trichodysplasia spinulosa pathology.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
Read the full study on jidonline.org →