50 citations
,
December 2017 in “British Journal of Dermatology” This study found that ECMs from papillary and dermal papilla fibroblasts support normal basement membrane formation, suggesting potential improvements for therapeutic biomaterials in skin engineering.
49 citations
,
January 2024 in “Regenerative Biomaterials” In this study, a novel electrospun dressing patch made with radially oriented PHBV nanofibers and loaded with berberine was shown to significantly accelerate diabetic wound healing in mice, achieving 100% wound closure in 18 days while also demonstrating improved mechanical and anti-inflammatory properties.
41 citations
,
January 2015 in “Burns & Trauma” This review discusses developments in tissue engineering for burn wound coverage and reconstructive surgery, reporting no new results but highlighting the need for further research into clinical effectiveness.
37 citations
,
December 2020 in “PLANT PHYSIOLOGY” In this study, the researchers identified a temperature-sensitive mutant in Arabidopsis thaliana, showing disrupted root hair formation and altered responses to plant hormone treatments at elevated temperatures.
37 citations
,
June 2019 in “Stem cells” This study found that extracellular vesicles from stimulated human dermal fibroblasts enhanced hair follicle growth ex vivo by activating dermal papilla cells and involving the Norrin and β-catenin pathways.
35 citations
,
January 2022 in “Clinical Infectious Diseases” This study found that healthcare workers with a positive COVID-19 test reported long COVID symptoms more frequently than negative controls, while prior physical activity was linked to reduced neurocognitive and fatigue symptoms.
35 citations
,
December 2017 in “Journal of Experimental Botany” In this study, CSLD3 overexpression in Arabidopsis enhanced root and hypocotyl growth by increasing cell elongation, with root growth highly sensitive to ethylene and phosphate starvation conditions.
34 citations
,
January 2022 in “Human Reproduction Open” This study found no clinically significant effects of intraovarian injection of platelet-rich plasma on ovarian function over one year in patients with extremely low functional ovarian reserve.
30 citations
,
July 2021 in “Annals of Botany” This study observed that maize plants enhance phosphorus acquisition by promoting both root hair growth and lateral root development in response to localized nutrient patches, highlighting a complementary root trait trade-off.
29 citations
,
January 2021 in “G3 Genes Genomes Genetics” This study identified a 195 bp duplication in crested chickens that causes large crest feathers and can be associated with cerebral hernia in some breeds, but not all.
28 citations
,
February 2021 in “Open Forum Infectious Diseases” This review highlights how social, environmental, and biological factors combine to increase COVID-19 risks in the African American community, emphasizing the need to understand these complex disparities; it reports no new results.
27 citations
,
May 2002 in “The Journal of Clinical Endocrinology & Metabolism” This study found that brothers of women with PCOS exhibit elevated DHEAS levels, indicating a potential familial genetic trait, but did not show increased rates of premature balding.
23 citations
,
December 2023 in “Skin Health and Disease” This study highlights a scarcity of data and treatment guidelines for vitiligo in Africa, the Middle East, and Latin America, emphasizing the need for regional epidemiological studies and tailored management approaches.
21 citations
,
March 2023 in “Journal of Crohn s and Colitis” This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.
21 citations
,
January 2020 in “Conservation Physiology” This study found that cortisol concentrations were significantly higher in hair samples with follicles compared to those without, suggesting potential confounding in stress assessments using different hair sampling methods.
18 citations
,
January 2024 in “Regenerative Biomaterials” This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.
15 citations
,
May 2023 in “Aesthetic Surgery Journal” This study highlights ongoing limitations in the administration and reporting of FACE-Q Aesthetic scale data, recommending that future research follow the User's Guide for proper administration and scoring, justify the study's time frame, and provide sample size calculations for key outcomes.
15 citations
,
January 2020 in “ILAR Journal” This review discusses the occurrence and impact of background histopathologic changes in nonhuman primate research, emphasizing the importance of understanding these factors to enhance study validity and interpretation.
14 citations
,
February 2021 in “Open Forum Infectious Diseases” In this study, 84% of postacute COVID-19 patients experienced at least one persistent symptom 60 days after hospital discharge, regardless of initial disease severity.
12 citations
,
November 2024 in “Burns & Trauma” This review highlights the critical role of neuroregulation in skin wound healing, emphasizing how neurotransmitters and neuropeptides regulate inflammation, angiogenesis, and cell proliferation, and discusses potential therapeutic strategies, such as neuromodulation, to enhance these processes.
12 citations
,
February 2020 in “The Journal of Clinical Endocrinology & Metabolism” This study found that a self-assessed modified Ferriman-Gallwey score of 10 or higher indicates excess body hair, and suggests androstenedione measurement should accompany testosterone when evaluating hyperandrogenism.
12 citations
,
August 2007 in “Human Molecular Genetics” This study found that Lymphotoxin-beta primarily influences periderm differentiation, impacting epidermal and hair follicle differentiation at later stages.
11 citations
,
January 2024 in “Regenerative Biomaterials” This research reported that a newly developed dually crosslinked gelatin-alginate-based hydrogel scaffold enhances mechanical strength, promotes corneal tissue regeneration, and reduces scarring in rabbit models, suggesting potential applications in corneal tissue engineering.
10 citations
,
January 2024 in “Burns & Trauma” This meta-analysis found that ADSC-Exo therapy can enhance healing in both general and diabetic wounds by promoting neovascularization, improving epithelization and collagen fiber deposition, and reducing scar formation, suggesting significant potential for clinical and research applications.
9 citations
,
April 2024 in “The Oncologist” This study found that sacituzumab govitecan improved health-related quality of life in most areas for patients with HR+/HER2− metastatic breast cancer compared to chemotherapy, except for increased diarrhea, supporting its use as a treatment option.
9 citations
,
March 2022 in “Journal of the Endocrine Society” This study found that testosterone more accurately predicts PCOS diagnosis than 11-oxyandrogens, which were linked with hirsutism severity and showed varying responses to contraceptive and metformin treatments.
9 citations
,
April 2019 in “Bioscience, biotechnology, and biochemistry” This research identified key miRNAs involved in sheep fetal hair follicle development, highlighting the prolactin signaling pathway and platelet activation as critical processes in secondary follicle initiation.
9 citations
,
April 2018 in “Biology of reproduction” This study concluded that dietary changes alter serum progesterone and estradiol levels in late gestation ewes, likely due to metabolism rather than changes in placental steroid synthesis.
9 citations
,
June 2016 in “Stem cells” In this study, overexpression of secretory phospholipase A2 Group-IIA in transgenic mice led to depletion of hair follicle stem cells and increased differentiation, linked to changes in histone modifications.
8 citations
,
March 2023 in “British Journal of Dermatology” This review highlights the significant role of next-generation sequencing in uncovering the genetic basis of hair disorders, identifying 28 nonsyndromic conditions linked to specific genes.