Subpopulations of Dermal Skin Fibroblasts Secrete Distinct Extracellular Matrix: Implications for Using Skin Substitutes in the Clinic

    December 2017 in “ British Journal of Dermatology ”
    Martina Ghetti, Helena Topouzi, Georgios Theocharidis … Claire A. Higgins
    Studysummary This study found that ECMs from papillary and dermal papilla fibroblasts support normal basement membrane formation, suggesting potential improvements for therapeutic biomaterials in skin engineering.
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    Research cited in this study 8

    1. Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles Experimental Dermatology · 2017
    2. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    3. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    4. The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization Experimental Dermatology · 2009
    5. Defining Hair Follicles in the Age of Stem Cell Bioengineering Journal of Investigative Dermatology · 2007
    6. Hair Cycle-Specific Expression of Versican in Human Hair Follicles Journal of Dermatological Science · 2005
    7. Cellular and Extracellular Involvement in the Regeneration of the Rat Lower Vibrissa Follicle Development · 1992
    8. Distribution of Extracellular Matrix Molecules in Human Hair Follicles Annals of the New York Academy of Sciences · 1991

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