October 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study found that the F6 formulation of a hair tonic containing EDS and ATG extracts produced the most significant hair growth in rabbits, without causing skin irritation and remaining stable throughout the observation period.
32 citations
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December 2013 in “Biological & Pharmaceutical Bulletin” In this study, rice bran supercritical CO2 extract demonstrated potential to promote hair growth in mice, increasing hair follicles and growth factor expression, similarly to 3% minoxidil.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses plant extracts for dermatological use, highlighting evidence that some can reduce edema in chronic venous insufficiency or help treat actinic keratoses, but it reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.
10 citations
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January 2018 in “Functional Foods in Health and Disease” This study found that berry extracts, especially black raspberry extract, may have anti-aging effects due to their high antioxidant activities.
4 citations
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August 2023 in “Journal of Cosmetic Dermatology” Gynostemma pentaphyllum extract may help grow hair and prevent graying.
January 2017 in “대한본초학회지(본초분과학회지)” This study found that Sinseon-yukza-hwan extract has strong antioxidative properties, effectively inhibiting free radical generation, which supports its potential use as a natural antioxidant.
January 2022 in “Healthy Tadulako Journal” This study found no difference in the physical stability of hair tonic preparations made from sansevieria leaves extract, regardless of whether maceration or soxhletation methods were used.
January 2023 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that a mixed extract of N. jatamansi, O. basilicum, and C. sativus, particularly when extracted via steaming and ultrasonic methods, increased antioxidant content, stimulated melanin production for black hair, and promoted hair growth in mouse models, while maintaining high cell viability.
2 citations
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April 2021 in “Asian pacific Journal of Tropical Biomedicine” This study found that Origanum vulgare extract significantly ameliorated finasteride-induced liver and kidney damage in mice by improving biochemical indices, reducing inflammation, and enhancing antioxidant status in a dose-dependent manner.
August 2015 in “아시안뷰티화장품학술지” This study found that ultrasonic (ethanol) extracts of Salvia miltiorrhiza bunge and Scutellaria baicalensis were most effective for cell proliferation, while ethanol and ultrasonic waves (water) methods had high antioxidant activity, suggesting their potential in functional cosmetics.
August 2025 in “Journal of the Korean Society of Cosmetology” In this study, a 5% Gymnema sylvestre leaf extract formulation applied to C3H mice showed significantly delayed hair regrowth by increasing TGF-β1 and TGF-β2 expression while reducing β-catenin levels, suggesting its potential as a natural hair growth inhibitor.
2 citations
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January 2002 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study found that Sophora flavescens extract promoted hair growth in mice by advancing the hair cycle and may inhibit acne-causing bacteria, though it did not affect in vitro hair follicle cell growth.
11 citations
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October 2015 in “Clinical and Experimental Dermatology” This study found that an extract from the root of Sophora flavescens Aiton significantly improved hair growth in patients with androgenetic alopecia over 6 months.
June 2025 in “Formosa Journal of Sustainable Research” In this study, the NADES extract of mangkokan leaves (Polyscias scutellaria) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with a total flavonoid content measured at 4.944 mgEQ/gSimplisia using the disc diffusion method.
This study found that pectin lyase-modified red ginseng extract (GS-E3D) may promote hair growth by enhancing antioxidant and anti-inflammatory effects, proliferating hair dermal papilla cells, and inhibiting 5α-reductase activity.
December 2022 in “한국 미생물 생명공학회지” TS-SCLF from fermented Schisandra chinensis may promote hair growth and improve hair quality.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” In this study, a new hair serum featuring Catharanthus roseus extract was formulated and evaluated, showing a stable and appealing product with potential hair growth-promoting properties, positioning it as a promising herbal alternative to synthetic agents like minoxidil.
1 citations
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June 2025 in “Pharmacognosy Research” This study found that a polyherbal sunscreen cream, F4, containing Camellia sinensis, Vitis vinifera, and Silybum marianum extracts demonstrated strong antioxidant and photoprotective properties, similar to synthetic sunscreens.
8 citations
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January 2024 in “Current Research in Food Science” This study found that using composite alginate hydrogels containing Aloe vera, CMC, and tragacanth can improve the encapsulation efficiency and protect pumpkin seed protein hydrolysates from degradation during simulated gastrointestinal digestion, potentially increasing their applicability as functional food components.
In this study, the SFE-4 extract from coffee pulp demonstrated potential effects for treating androgenetic alopecia by enhancing cell proliferation and gene expression related to hair growth pathways in vitro, using human hair follicle dermal papilla and prostate cancer cells.
9 citations
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April 2019 in “Molecules” This study found that a blackcurrant extract with phytoestrogen activity increased hair number and stem cell marker expression in a menopausal rat model, suggesting a potential benefit for hair loss.
4 citations
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December 2012 in “Journal of the Society of Cosmetic Scientists of Korea” This study found that a medicinal herbal complex extract increased hair growth and cell proliferation in vitro and in C57BL/6 mice, suggesting it could be useful for enhancing hair growth.
May 2026 in “International Journal of Molecular Sciences” In this study, a new formulation of human placental extract showed antioxidant and neurite outgrowth activities, significantly reduced hair graying in mice, and alleviated neuropathy symptoms, suggesting potential therapeutic benefits.
1 citations
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January 2024 in “Journal of Food Processing and Preservation” This study found that adding microcapsulated pumpkin seed protein hydrolysate to aloe vera drinks improved antioxidant activity, taste, and shelf life, with chitosan-alginate microcapsules effectively inhibiting microbial growth during 30 days of refrigerated storage.
In this study, the ethanol extract of Tridax procumbens leaves exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria, with specific active compounds identified through GC-MS analysis that may contribute to its therapeutic potential.
This study focused on extracting compounds from curry leaves using various methods and evaluated the extract's purity, solubility, and stability, suggesting potential health benefits like improved digestion and hair growth.
December 2023 in “International Journal of Health and Pharmaceutical” This study investigated the effects of a derma pen treatment using green betel leaf extract cream on hair development in female Wistar rats, highlighting the antioxidant and anti-inflammatory properties of betel leaves that may aid in hair growth and condition.
April 2021 in “Journal of Investigative Dermatology” This study suggests that edelweiss extract may promote hair growth and reduce shedding in ex vivo experiments by affecting hair follicle anagen phase duration and keratinocyte proliferation.
3 citations
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July 2015 in “International journal of pharmacology” In this study, Natural Plant Extracts (NPE) promoted hair growth in mice by stimulating anagen growth and upregulating relevant gene expression, compared to controls with saline.