December 2021 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” This study concluded that hair tonic formulations using extracts of green tea leaves, celery leaves, or their combination can effectively promote hair growth in guinea pigs, with the fastest growth seen using a 2.5% green tea to 7.5% celery leaf extract ratio.
In this case report, interferon-alpha treatment for a man with hemophilia and hepatitis C was associated with unexpected diffuse hair growth, likely caused by the medication.
December 2025 in “Sustainable Chemistry One World” In this study, researchers found that mangosteen pericarp extract, combined with FeSO₄ as a mordant, effectively produced a stable reddish hair dye on bleached hair, with good color persistence and enhanced tensile strength, indicating its potential as an eco-friendly and safer alternative to synthetic dyes.
1 citations
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January 2025 in “Reproductive Biology and Endocrinology” This study suggests that supplementing with a cell-free fat extract might enhance embryo development and improve clinical outcomes in older women experiencing in vitro fertilization failure.
November 2025 in “Journal of English Language and Education” In this study, researchers found that a hair tonic formulated with 2% guava leaf extract demonstrated strong consumer acceptance and safe physicochemical characteristics among university students, showing potential as a natural alternative for reducing hair loss.
April 2025 in “Jurnal Analis Farmasi” This study evaluated hair tonic formulations containing Ambon banana peel extract and found that the preparation, particularly at an 8% concentration, significantly promoted hair growth compared to other formulations, though it still differed from the control group's effectiveness.
14 citations
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January 2015 in “Clinical Nutrition Research” This clinical trial found that the extract complex of Cistanche tubulosa and Laminaria japonica (MK-R7) significantly improved hair density and diameter in patients with patterned hair loss over 16 weeks.
August 2021 in “Majalah Obat Tradisional” This study found that a hair tonic formulated from green tea extract showed similar hair growth-promoting activity to 2% Minoxidil in rabbits, without causing skin irritation or bacterial contamination.
4 citations
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January 2018 in “Cosmetics” This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.
September 2026 in “medRxiv” This study found that the combination of recombinant growth factors and plant-derived extracellular vesicles significantly improved scalp regulation, hair growth, thickness, and density, and reduced hair shedding in the tested formulation by Day 56.
December 2017 in “JURNAL FARMANESIA” In this study, the researchers found that using dragon fruit peel extract in a gray hair dye formulation, along with specific adjuvants, produced a dark black color on gray hair, demonstrating its potential as a natural colorant alternative to synthetic dyes.
This study found that Avicennia marina extract significantly increased hair growth in androgenic alopecia patients, suggesting its potential effectiveness by inhibiting 5 alpha-reductase and regulating relevant growth factors.
13 citations
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December 2011 in “Korean Journal of Food Science and Technology” This study suggests that black soybean extract promotes hair growth and improves scalp health by enhancing blood circulation and cellular proliferation, although further human studies are needed to verify these effects.
75 citations
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October 2002 in “Journal of Dermatological Science” This study found that Sophora flavescens extract may promote hair growth in mice by inducing earlier hair cycle changes and regulating growth factors in dermal papilla cells.
4 citations
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June 2011 in “Journal of Biomedical Research” This study suggests that a herbal extract from Gardenia, Mentha arvensis, Rosemary, and Lavender may promote hair growth in mice at a rate comparable to minoxidil.
August 2019 in “Pharmacoscript” This study found that a combination of pandanus and sansevieria leaf extracts at a 3:2 ratio showed improved hair growth activity compared to individual extracts and controls.
1 citations
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April 2014 in “Dong-ui saengni byeongni hakoeji/Dong'ui saengli byeongli haghoeji” This study indicates that Samhwang-Sasimtang ethanol extract may promote hair growth in a mouse model, showing stronger effects than a control but less than 3% minoxidil.
August 2019 in “Key engineering materials” This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.
4 citations
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January 2011 This study found that Pleuropterus cilinervis extracts and animal milk fermented with Lactobacillus rhamnosus promoted hair growth in mice, suggesting potential applications in hair loss treatments.
16 citations
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September 2022 in “International Journal of Molecular Sciences” This study reported that Juniperus sabina needle extract showed significant anti-butyrylcholinesterase activity, suggesting potential medicinal value due to high podophyllotoxin levels.
19 citations
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March 2020 in “Journal of Functional Foods” This study found that golden silk mature silkworm powder improved cognition and neuron proliferation in mice, potentially by enhancing mitochondrial function and countering scopolamine-induced amnesia.
This study found that the herbal extract CS-10-H, like minoxidil, significantly improved hair growth, density, and thickness in a mouse alopecia model.
2 citations
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January 2020 Certain dietary supplements can improve hair health.
In this study, mangosteen pericarp extract was found to promote hair dermal papilla cell proliferation and enhance melanin synthesis, suggesting its potential as an ingredient in hair growth and tanning products.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.
December 2025 in “International Journal of Molecular Sciences” This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.
This study found that administering drumstick leaves extract with amla powder improved hemoglobin levels among adolescent girls with anemia at a residential facility in Trichy.
2 citations
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April 2021 in “Journal of Cosmetic Dermatology” This study found that sulforaphane and its related compounds may promote hair follicle growth in mice, suggesting their potential as treatment agents for androgenic alopecia.
July 2012 in “EFSA supporting publications” This technical report from the European Food Safety Authority responds to comments on its previous scientific opinion regarding a health claim about spermidine and hair growth, reporting no new experimental results.
August 2022 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” This study found that a combination of H. rosa-sinensis L. and B. racemosa extracts produced the most hair follicles in stress-induced alopecia in male Wistar albino rats.