7 citations
,
January 2022 in “Brazilian Journal of Biology” This study found that a shampoo formulation using mangabeira leaf extract without sodium lauryl sulfate showed promising antioxidant activity and improved foam quality.
January 2011 in “Zhongguo nongye Kexue” This study successfully established a transgenic sheep fibroblast cell line expressing the spider dragline silk protein gene, laying groundwork for developing transgenic sheep with this capability in hair follicles.
4 citations
,
May 2019 in “Zeitschrift für Naturforschung C” This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.
1 citations
,
May 2023 in “International Journal of Applied Pharmaceutics” In this study, the researchers developed a novasome vesicle carrying bovine placenta extract, which demonstrated superior hair growth effects in rats compared to traditional minoxidil and PE-loaded liposomes, and showed good stability and physical characteristics over 90 days at 4°C.
December 2025 in “Journal of Food and Pharmaceutical Sciences” This study found that extracts and crude protein from the white oyster mushroom demonstrated significant thrombolytic activity compared to a positive control, suggesting their potential as natural thrombolytic agents for thromboembolism therapy.
1 citations
,
September 2008 In this study, herbal extracts were associated with increased hair regrowth in mice when compared to the negative and vehicle control groups, potentially due to enhanced activity of certain enzymes and growth factors.
1 citations
,
August 2024 in “Pharmaceuticals” This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.
December 2021 in “Jurnal ilmiah Manuntung” This study tested a hair tonic containing gotu kola and garlic extracts on rabbits, finding that the formulation with 5% gotu kola and 0.04% garlic showed promising hair growth results and remained stable during storage.
December 2025 in “International Journal of Molecular Sciences” In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.
4 citations
,
August 2017 in “Cosmetics” This study observed that Biota orientalis L. leaf extract may promote hair growth and suppress sebum production in human cells, suggesting potential benefits for hair restoration.
Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.
1 citations
,
January 2020 in “Journal of Biosciences and Medicines” This study found that a 5% gel with hydroalcoholic extract from black pop bean integument may have a photoprotective effect in mice exposed to UV-C radiation.
January 2002 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study found that several natural extracts, including Prunus mume and Rubi Fructus, showed hair growth-promoting effects in mice, but none significantly impacted human hair dermal papilla cells in vitro.
February 2025 in “Journal of Fundamental and Applied Pharmaceutical Science” In this experimental study, the researchers developed and evaluated a hair tonic made from mangosteen peel extract, finding that all four tested formulations showed suitable physical characteristics and met standard requirements for attributes like pH, viscosity, and stability.
188 citations
,
December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
June 2026 in “Current Issues in Molecular Biology” In this study, a botanical extract and minoxidil showed similar effects in vitro by reducing pro-inflammatory cytokines and 5α-reductase expression while increasing growth factors VEGF and KGF in human keratinocyte cells, suggesting potential for further in vivo research.
January 2024 in “International Journal of Pharmacognosy and Pharmaceutical Research” This review highlights the potential of plant-derived molecules like Epigallocatechin-3-Gallate and Ginsenosides to promote healthy hair growth by enhancing nutrient supply and blood flow to the scalp, and notes their growing role in natural hair care product development.
1 citations
,
November 2021 in “Jurnal Farmasi Indonesia” In this study, three hair tonic formulas containing Kayu Secang extracts demonstrated hair growth activity in rabbits, with the chloroform-methanol fraction showing the most significant results.
January 2025 in “MEDS Public Health and Preventive Medicine” In this study, oral spermidine supplementation was found to significantly prolong the hair follicle anagen phase and reduce hair loss, with effects persisting three months after treatment in healthy participants, suggesting potential therapeutic benefits for hair loss conditions.
4 citations
,
August 2024 in “International Journal of Molecular Sciences” This study found that a combination of natural compounds (escin, bromelain, ginkgo biloba, and sage miltiorrhiza) reduced platelet adhesion to activated endothelium in laboratory settings by inhibiting adhesion molecule transcription and reducing pro-inflammatory cytokines, potentially preventing initial steps of the coagulation cascade.
January 2021 in “AIP conference proceedings” This research found that the most cost-effective extraction for developing a coffee-based hair serum is from fall grade cherry coffee, which balances active ingredient content and material cost effectively.
June 2026 in “International Journal of Drug Delivery Technology” This study developed EGCG-loaded nanohydrogels using ethyl cellulose and polyvinyl alcohol to enhance the stability and delivery of the hydrophilic drug in aloe vera gel, optimizing encapsulation efficiency and drug release properties.
August 2009 in “한국실험동물학회 학술발표대회 논문집” Fermented Rhus Verniciflua Stokes Extract may help hair grow in cells and mice.
June 2023 in “MPI (Media Pharmaceutica Indonesiana)” This systematic literature review identified kale leaf hair tonic (Ipomoea aquatica Forsk.) at 5% concentration as an effective herbal cosmeceutical preparation for enhancing hair growth, showing an average increase in hair length over 21 days, while meeting established pharmaceutical standards.
This study found that PLX, a mixture of tomato extract and chitooligosaccharide, may reduce prostate weight in testosterone-induced BPH in rats, suggesting it could act as a 5α-reductase inhibitor.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” This study reports the successful formulation of a stable herbal hair serum with Catharanthus roseus extract and other ingredients, noting it has a suitable pH, consistency, and stability, suggesting potential effectiveness as a natural alternative for hair care pending further clinical trials.
1 citations
,
October 2015 in “CRC Press eBooks” Nutricosmetics with active ingredients can help with hair loss and improve hair growth.
April 2025 in “The Journal of Agriculture and Development” In this study, researchers optimized the extraction conditions for polyphenols from the medicinal herb Eclipta prostrata, achieving the highest polyphenol content under specific conditions of temperature, solvent concentration, and time, and found the extract to have significant antioxidant activity.
August 2019 in “Pharmacoscript” This study found that a 3:2 combination of pandanus and sansevieria leaf extracts showed the best hair growth activity compared to using each extract alone.
17 citations
,
August 2010 in “International Journal of Cosmetic Science” This study found that a cosmetic formula containing 2% Orthosiphon stamineus leaf extract significantly reduced skin oiliness and pore size, showing better results than a formula with 1% zinc gluconate.