August 2015 in “Dermatologica Sinica” This study found that young adult men with moderate to severe AGA have poorer semen quality compared to those with normal to mild AGA.
1 citations
,
January 2010 in “Clinica Veterinaria De Pequenos Animales” In this case report, treatment with antibiotics, finasteride, and prostate omentalization restored fertility in a 6-year-old German Shepherd with prostatitis and astenoteratozoospermia, avoiding surgical castration.
2 citations
,
October 2001 in “Mycoses” This study confirmed that a rare dermatophyte infection in a young cat was caused by Arthroderma gypseum, identified using molecular analyses.
70 citations
,
February 2016 in “EMBO reports” This study identified a subtype of itch-sensing neurons in mice, which express Ret and somatostatin, and found that their ablation reduces scratching induced by certain pruritogens.
7 citations
,
June 2015 in “The anatomical record” This study in Hexi cashmere goats found that secondary follicle activity increases with time, and Hoxc13 expression varies significantly across different growth stages, suggesting a role in follicle activity.
January 2001 in “亚洲男性学杂志:英文版” This review discusses hormonal changes in aging men and suggests the need for more research on androgen supplementation and partial androgen deficiency, without presenting new clinical findings.
30 citations
,
January 1999 in “Journal of Cutaneous Pathology” This study suggests that spiny keratoderma may be an ectopic hair formation on palms and soles, based on keratinization patterns observed using antikeratin antibodies and electron microscopy.
April 2017 in “Journal of Investigative Dermatology” This study found that hair follicle matrix progenitors differentiate into various layers asynchronously, with early progenitors forming the companion layer and later progenitors generating the inner root sheath and hair shaft.
April 2026 in “Experimental & Molecular Medicine” This study used integrated single-cell chromatin and transcriptomic analyses in developing mouse skin to uncover gene networks involved in skin lineage specification and identified Mef2c+ upper fibroblasts as potential precursors to certain muscle-like structures, with cross-species findings in human skin.
July 2021 in “Asia-Pacific journal of convergent research interchange” This research on dermal papilla cells found that Sparasis crispa increased mRNA expression related to hair production and may help in hair generation cycles, but its impact on male hair loss treatment remains uncertain.
April 2019 in “Journal of Investigative Dermatology” This study reported that mSKPs and DMSCs share similarities in biological characteristics but exhibit distinct transcriptome profiles, with mSKPs being more immune-related and DMSCs more associated with differentiation and disease pathways.
8 citations
,
March 2009 in “Differentiation” The study demonstrated that bulge stem cells from rat vibrissa follicles respond to adult dermal papilla signals, inducing hair bulb formation and regenerating hair structures in vivo.
January 2006 in “Zhonghua miniao waike zazhi” This study established a stable rabbit model of hypospadias using finasteride, finding varied rates of the condition's severity and associated testicular retention across different gestation day treatments.
9 citations
,
October 2017 in “Translational pediatrics” This review examines the skin manifestations of various endocrine disorders, highlighting their underlying pathophysiology and impact on an individual's health and quality of life, without reporting new research findings.
143 citations
,
August 1991 in “Endocrinology” This study found that blocking androgen receptors inhibits testicular descent in rats more effectively during the early stages of gubernacular outgrowth than inhibiting 5a-reductase.
20 citations
,
February 2010 in “Journal of Investigative Dermatology” Slug (Snai2) helps regulate hair growth timing in mice.
3 citations
,
April 2012 in “Cancer research” This study reports that side-population stem cells, distinct from hair follicle stem cells, may play a significant role in the malignant progression of squamous cell carcinomas in mice.
August 2024 in “Microscopy Research and Technique” This study described the structure of the hair brush on male Endoclita vietnamensis moths' legs, identifying characteristics such as specialized scales and a pheromone gland, which could facilitate the future development of pheromone-based pest control methods for eucalyptus pests in China.
April 2020 in “The FASEB Journal” This study identified specific genes and pathways in human Leydig cells that may contribute to Post-finasteride Syndrome, potentially informing future treatments to reverse persistent side effects.
16 citations
,
January 2005 in “The International Journal of Developmental Biology” This study found that Hex gene expression patterns in chick embryo dorsal skin during feather bud development suggest a significant role in initiating feather morphogenesis.
36 citations
,
June 1988 in “Australian Journal of Biological Sciences” This study found that twice-daily intradermal injections of mouse epidermal growth factor in Merino sheep resulted in dose-dependent changes in wool follicles and fibres, including induction of catagen and subsequent regeneration.
4 citations
,
October 2020 in “Toxicology Mechanisms and Methods” This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.
33 citations
,
December 2004 in “Differentiation” In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.
33 citations
,
October 2013 in “PloS one” This study found that human sweat glands contain unique stem cells with significant multilineage differentiation potential and self-renewal abilities, suggesting promising clinical applications due to easy biopsy access.
16 citations
,
May 2000 in “Endocrinology” This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.
26 citations
,
May 2011 in “Tissue Engineering Part A” This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.
27 citations
,
January 2010 in “Animal” In these studies, researchers found that Peruvian camelids reach mature skin follicle development early, with specific cuticular characteristics useful for distinguishing fleece types, while Bolivian llamas have a mature follicle apparatus present at birth.
January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.
1 citations
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January 1971 in “Acta dermato-venereologica” Mice hair follicles take in the amino acid cystine.