Fertility and Sexual Life of Men After Their Forties and in Older Age

The document discussed the effects of aging on male fertility and sexual health, noting that while spermatogenesis can continue into old age, only about 50% of men in their eighties experienced complete loss of fertility. Aging in men was characterized by a decline in Leydig cells, altered sex hormone levels, and impaired pituitary-gonadal feedback, leading to increased LH and FSH levels and reduced testosterone bioavailability. Men over 60 often showed signs of reduced virility, such as decreased muscle mass, strength, sexual hair growth, and libido. The document suggested that androgen supplementation could be beneficial, but highlighted the need for more research and precise epidemiological data on partial androgen deficiency in aging males (PADAM) due to a lack of long-term risk-benefit studies.