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This study found that the evodiamine derivative 2-16 exhibited the highest antitumor activity and a broad spectrum of activity against various human cancer cell lines, with improved solubility.

This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.

This study found that the dissolution profiles of different finasteride polymorphs may affect the quality of finasteride capsules, highlighting the need for polymorphic quality control.

This study found that 3-aminopropyltriethoxysilane penetrates hair fibers and improves the mechanical resistance of dry hair, addressing the needs for increased body in fine hair.

This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.

This study found that a bioactive borosilicate glass containing Sr and Cu ions exhibited promising mechanical strength, biocompatibility, and antibacterial activity, particularly the CuSr-1 wt.% composition, suggesting potential for use in orthopedic implants and bone tissue engineering.

This study analyzed hair styling mousses on the Slovenian market, finding that their formulations primarily rely on polymers, with no banned ingredients according to European cosmetics regulations.

This research describes a process for producing caffeine nanocrystals, which may enhance skin penetration by accumulating in hair follicles and maintaining stability for two months, paving the way for in vivo testing.

In this study, researchers developed microcapsules and effervescent tablets containing policosanol from insect wax, achieving high encapsulation efficiency and rapid water dispersion, effectively addressing the challenges of solubility and psychological acceptance in consuming insect-based lipids.

This study found that the dimethyl-β-cyclodextrin inclusion system significantly improved the solubility and bioavailability of finasteride compared to the drug alone, enhancing its absorption rate.

This study evaluated the stability of multiple active ingredients in TrichoSol™ for use in alopecia treatments, finding varying stability durations at room temperature—up to 180 days for some ingredients—supporting its use as a compounding vehicle in personalized therapies.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This study investigated improving Finasteride's water solubility using trimethyl-β-cyclodextrin (TM-β-CD) and β-cyclodextrin (β-CD) as carriers, finding that β-CD improved Fin's cumulative release, while TM-β-CD enhanced its solubility, with computational data supporting these outcomes.

Poly(ethylene-co-vinyl alcohol) monoliths can be made using heat separation for various uses.

This study isolated highly pure oleanolic and maslinic acids from olive milling residues, exploring their chemical reactions, including the formation of finasteride precursors.

This study developed a solid shampoo formulation with conditioning properties, highlighting its feasibility and environmental benefits compared to conventional shampoos due to biodegradable packaging and no water in its composition, thus offering a sustainable alternative in the cosmetic industry.

This study reports a novel method for synthesizing substituted hydantoins, including the anticonvulsant drug ethotoin, using safer reagents and fewer steps compared to conventional protocols.

This review discusses five potential mechanisms for kidney stone formation, including urinary supersaturation, Randall's plaques, sex hormones, the microbiome, and immune responses, and reports no new results.

This study identified two types of calcium in human scalp hair shafts: easily removable calcium, likely as calcium soaps, and more stably bound calcium, possibly related to Ca-binding proteins.

This study found that incorporating a block copolymer significantly alters the size and morphology of niosome drug delivery systems made of non-ionic surfactants and cholesterol, affecting their stability.

This study developed and validated a sensitive method using adsorptive cathodic stripping voltammetry to directly determine minoxidil in topical solutions, shampoos, and creams, achieving high recovery rates and precision.

This study found that 1-butyl-3-methylimidazolium tetrafluoroborate is the optimal ionic liquid solvent for extracting quercetin from Nothopanax scutellarium leaves.

This study found that stilbamidine and hydroxystilbamidine can inhibit the release of specific enzymes from lysosomes and mitochondria in rabbit liver at certain concentrations, with effects similar to cortisol and chloroquine.

This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.

This study found that freeze-dried finasteride nanoparticles significantly improved the dissolution rate and pharmacokinetic parameters compared to pure drug formulations, suggesting enhanced stability and solubility for poorly water-soluble drugs.

New, cheaper method measures finasteride in tablets accurately and quickly.

This study reported that both Sterculia villosa bark and Vernonia patula plant extracts showed concentration-dependent antioxidant activities, with Vernonia patula demonstrating a stronger effect.