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210-240 / 1000+ resultsresearch Spermine Lipid Assembled Nanoparticles for siRNA Delivery and Androgenetic Alopecia Therapy
In this study, Sper-12/siRNA nanoparticles effectively suppressed abnormal AR protein levels, promoted hair follicle proliferation, and alleviated hair loss symptoms in androgenetic alopecia model mice, providing a promising delivery platform for siRNA-based therapeutics.
research Effects of Microwave-Assisted Opuntia humifusa Extract in Inhibiting the Impacts of Particulate Matter on Human Keratinocyte Skin Cell
This study found that microwave-assisted Opuntia humifusa extract improved antioxidant and anti-inflammatory properties to counteract particulate matter's harmful effects on HaCaT keratinocytes.
research Quality-by-design based peppermint oil-loaded self-micro emulsifying drug delivery system for the management of androgenetic alopecia
This study reported that a novel SMEDDS formulation of PPO demonstrated better permeation and improved hair growth compared to a marketed formulation in tests for managing androgenetic alopecia, with further exploration suggested.
research Assessment of in vitro anti-inflammatory, hemostatic, antimicrobial, photoprotective and antioxidant activities of the Algerian species Suaeda monodiana
This study found that the methanolic extract of Suaeda monodiana Maire exhibited antioxidant, antimicrobial, and photoprotective activities, suggesting its potential use in pharmaceutical formulations for treating skin diseases.
research A Preview of Selected Articles
This paper reviews the role of miRNAs in stem cell therapies and hair follicle growth, reporting no new findings but highlighting recent insights into fertility treatment and wound healing.
research Minoxidil niosome loaded dissolving microneedle delivery system for treatment of DHT induced androgenic alopecia in C57BL/6 Mice
research Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Rescue the Loss of Outer Hair Cells and Repair Cochlear Damage in Cisplatin-Injected Mice
In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.
research Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling
This study found that selective androgen receptor modulators (SARMs) significantly inhibited tumor growth and metastasis-promoting factors in AR-positive triple-negative breast cancer models.
research Identification of microRNAs involved in growth arrest and cell death in hydrogen peroxide-treated human dermal papilla cells
In this study, transcriptome analysis identified 68 differentially expressed miRNAs in human dermal papilla cells treated with hydrogen peroxide, suggesting they play a significant role in growth arrest and apoptosis.
research Bio-Pulsed Stimulation Effectively Improves the Production of Avian Mesenchymal Stem Cell-Derived Extracellular Vesicles That Enhance the Bioactivity of Skin Fibroblasts and Hair Follicle Cells
This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.
research Cardamonin inhibits the expression of inflammatory mediators in TNF-α-stimulated human periodontal ligament cells
This study found that cardamonin can reduce inflammation in TNF-α-stimulated human periodontal ligament cells by suppressing specific cytokines and chemokines and inhibiting key inflammatory signaling pathways.
research ZmSPL10, ZmSPL14 and ZmSPL26 act together to promote stigmatic papilla formation in maize through regulating auxin signaling and ZmWOX3A expression
In this study, researchers identified that three homologous genes—ZmSPL10, ZmSPL14, and ZmSPL26—are crucial for the development of stigmatic papilla in maize, with triple knockout mutants lacking these genes showing almost no stigmatic papilla and significantly reduced kernel setting.
research Hair Tissue Mineral Analysis and Metabolic Syndrome
research Multimodal Recruitment for an Internet-Based Pilot Study of Ovulation and Menstruation (OM) Health
In the Ovulation and Menstruation Health Pilot Study, multimodal recruitment strategies effectively increased racial diversity and survey completion rates for studying menstrual disorders like PCOS.
research 712 A small molecule modulator of the wnt pathway (SM04554) as a potential topical treatment for androgenetic alopecia (AGA)
This study found that the novel IPC analog SIG-1451 may inhibit inflammatory cytokine release in cell-based assays relevant to allergic dermatitis.
research Modulation of Electroosmotic Flow through Skin: Effect of Poly(Amidoamine) Dendrimers
This study found that polyamidoamine dendrimers can permeate skin's current conducting pores and alter the magnitude and direction of electroosmotic flow, affecting drug flux during iontophoresis.
research Delivery of minoxidil encapsulated in cyclodextrins with photoacoustic waves enhances hair growth
This study reported that using photoacoustic waves to enhance transdermal delivery of encapsulated minoxidil can significantly increase hair growth while reducing treatment frequency and systemic side effects.
research miR‐124 promotes neural differentiation in mouse bulge stem cells by repressing Ptbp1 and Sox9
This study found that miR-124 may facilitate the differentiation of hair follicle stem cells into neuronal cells by targeting Sox9 and Ptbp1.
research scMC learns biological variation through the alignment of multiple single-cell genomics datasets
This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.
research Antioxidant and Anticancer Activities of Anethum graveolens L., Citrus limon (L.) Osbeck and Zingiber officinale Roscoe Essential Oils
This study observed that Citrus limon essential oil demonstrated significant anticancer activity against an MCF-7 breast cancer cell line, suggesting its potential as a complementary cancer treatment.
research Targeted delivery of siRNA to human cancer and human embryonic stem cells with cell level resolution
This study demonstrated that a light-activated RNAi approach using hollow gold nanoshells effectively targets human prostate cancer cells with reduced off-target toxicity and material use compared to standard methods.
research Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing
This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.
research New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies
In this study, using a lotion containing N1-methylspermidine and Sandalore® for 3 months significantly reduced hair loss and stimulated hair growth in both men and women with chronic telogen effluvium, with benefits persisting 3 months after treatment ended.
research Smart DNA biosensor for in vitro detection of androgen receptor mRNA
This study developed a novel Smart DNA Biosensor for easy and efficient primary diagnosis of androgen receptors overexpression, which may aid in the rapid differential diagnosis of conditions like acne and androgenetic alopecia.
research Substantivity and After‐Rinsing Hair Growth Promotion of Cationic Microparticles of Minoxidil
This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.
research Analysis of the Long Non-Coding and Messenger RNA Expression Profiles in the Skin Tissue of Super Merino and Small-Tailed Han Sheep
In this study, researchers analyzed skin tissue from two sheep breeds during the growing period and identified 56 differentially expressed lncRNAs and 616 mRNAs linked to hair follicle development, suggesting potential targets for improving sheep wool quality through genetic and molecular approaches.
research Strengthening Roots, Reducing Hair Fall, and Reviving Scalp Health Through Botanical Innovation
This source describes the SwaLife Onion Shampoo as an Ayurvedic-dermatological formulation intended to nourish the scalp, strengthen hair roots, and enhance hair thickness and shine through a blend of onion extract and botanicals, without reporting specific study results.
research MicroRNA control of signal transduction
This review discusses the potential regulation of signal transduction pathways by microRNAs in animal cells, aiming to identify biological processes that may be influenced by miRNA-mediated regulation, but it reports no new experimental outcomes.
research Recyclable PolymerizableDeep Eutectic Solvent-BasedThree-Dimensional-Printed Dissolving Microneedles with pH-ResponsiveDelivery of ZIF-8-Loaded Minoxidil for Hair Loss Therapy
This study developed a novel, 3D-printed dissolving microneedle system for delivering minoxidil to treat hair loss, which showed pH-triggered drug release and enhanced hair regrowth in an alopecia mouse model, offering a potentially sustainable and safe transdermal therapy option.