Modulation of Electroosmotic Flow Through Skin: Effect of Polyamidoamine Dendrimers
January 2018
in “
Biomolecules & therapeutics
”
polyamidoamine dendrimers electroosmotic flow skin acetoaminophen generation 1 dendrimers generation 4 dendrimers generation 7 dendrimers methanol confocal microscopy fluorescein isothiocyanate viable epidermis dermis hair follicle anodal current iontophoresis PAMAM dendrimers EOF G1 dendrimers G4 dendrimers G7 dendrimers FITC
Studysummary This study found that polyamidoamine dendrimers can permeate skin's current conducting pores and alter the magnitude and direction of electroosmotic flow, affecting drug flux during iontophoresis.
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