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    Did you mean Small Molecule Inhibitor?
    Glossary Small Molecule Inhibitor

    blocks specific proteins or enzymes within cells

    A Small Molecule Inhibitor (SMI) is a type of drug that can enter cells easily due to its low molecular weight and can interfere with specific proteins or enzymes to block their activity. These inhibitors are often used in treatments for various diseases, including cancer and autoimmune disorders, by targeting and disrupting specific pathways that contribute to disease progression.

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    Research 30 of 1000+

    1. Chemotherapy-induced iatrogenic injury of skin: New drugs and new concepts Clinics in Dermatology · 2011 · 19 citations
    2. Molecular Targeted Agents and Biologic Therapies for Non-small Cell Lung Cancer Journal of thoracic oncology · 2010 · 12 citations
    3. Molecular targeted therapies for cancer: Sorafenib mono�therapy and its combination with other therapies (Review) Oncology Reports · 2012 · 46 citations
    4. Patient‐Level Adverse Event Patterns in a Single‐Institution Study of the Multi‐Kinase Inhibitor Sorafenib Clinical and translational science · 2016 · 10 citations
    5. Cutaneous reactions to chemotherapeutic drugs and targeted therapy for cancer Journal of the American Academy of Dermatology · 2014 · 88 citations
    6. Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling Cell Reports Medicine · 2026
    7. Cutaneous toxicities of new targeted cancer therapies: must know for diagnosis, management, and patient-proxy empowerment Annals of palliative medicine · 2019 · 7 citations
    8. The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma Current Dermatology Reports · 2013 · 6 citations
    9. Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology Clinical & Translational Oncology · 2018 · 26 citations
    10. Adverse Hair Reactions to New Targeted Therapies for Cancer Actas Dermo-Sifiliográficas · 2019 · 1 citations
    11. Management of Toxicities of Targeted Therapies Elsevier eBooks · 2018 · 2 citations
    12. Cutaneous drug reactions Elsevier eBooks · 2010 · 1 citations
    13. EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management Oncology and therapy · 2017 · 29 citations
    14. Spotlight commentary: Navigating the cutaneous side effects of chemotherapy British Journal of Clinical Pharmacology · 2025
    15. Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress International journal of biological sciences · 2023 · 2 citations
    16. Cutaneous adverse events to systemic antineoplastic therapies: a retrospective study in a public oncologic hospital Anais Brasileiros de Dermatologia · 2021 · 7 citations
    17. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    18. PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands Journal of Experimental & Clinical Cancer Research · 2025 · 7 citations
    19. Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models Frontiers in Oncology · 2024 · 17 citations
    20. Alopecia in patients treated with molecularly targeted anticancer therapies Annals of Oncology · 2015 · 44 citations
    21. Index 2013
    22. Anagen effluvium Indian Journal of Dermatology, Venereology and Leprology · 2013 · 61 citations
    23. Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review International Journal of Medical Sciences · 2025 · 4 citations
    24. Hair Changes due to Drugs Elsevier eBooks · 2018
    25. Pre-clinical non-viral vectors exploited for<i>in vivo</i>CRISPR/Cas9 gene editing: an overview Biomaterials Science · 2022 · 23 citations
    26. Drug eruptions in dermatology Expert Review of Dermatology · 2011 · 11 citations
    27. Corrective and Restorative Dermatology in Cancer Survivors: An Urgent Unmet Need! American Journal of Clinical Dermatology · 2026
    28. Understanding, recognizing, and managing toxicities of targeted anticancer therapies Ca · 2013 · 278 citations
    29. Therapies and nanotherapies for cervical cancer (Review) Biomedical Reports · 2025 · 3 citations
    30. Combinatorial Therapy of Letrozole- and Quercetin-Loaded Spanlastics for Enhanced Cytotoxicity against MCF-7 Breast Cancer Cells Pharmaceutics · 2022 · 39 citations