research Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle
Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
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research Premature Adrenarche, Polycystic Ovary Syndrome, and Intrauterine Growth Retardation: Does a Relationship Exist?
Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research Topical Immunotherapy in Alopecia Areata
Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.
research Physicochemical Properties of pH-Sensitive Hydrogels Based on Hydroxyethyl Cellulose–Hyaluronic Acid for Transdermal Delivery Systems for Skin Lesions
The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
research The Microbiome in Patients with Atopic Dermatitis
People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
research Permanent Makeup Removal Severe Complication: Case Report and Proposal of the Protocol for Its Management
Permanent makeup can cause delayed allergic reactions, but they can be managed with proper treatment.
research Sleep Quality and Its Clinical Associations in Trichotillomania and Skin Picking Disorder
People with trichotillomania or skin picking disorder generally sleep worse than those without these conditions.
research 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration
4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer
Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research Wound Microbiota and Its Impact on Wound Healing
Wound healing is greatly affected by the types of bacteria present, which can either help or hinder the process.
research Zinc in the Soil and Its Importance for Plants and Human Health: An Integrated Review
Zinc is essential for plant growth and human health, but many soils lack enough zinc, affecting crops and potentially leading to health problems.
research Hair Cortisol: A Biomarker of Chronic Stress in Animals and Its Association With Reproduction
High levels of cortisol in hair show long-term stress which can lower fertility in animals.
research Quantification of the Vitamin D Receptor-Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
research Effects of FGF5-Mediated LncRNA on the Skin Fibroblast Growth of Liaoning Cashmere Goats
FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Quality Evaluation of the Finasteride Polymorphic Forms I and II in Capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research Human Dermal Stem Cells Differentiate Into Functional Epidermal Melanocytes
Human dermal stem cells can become functional skin pigment cells.
research The Effects of Lovastatin on Conventional Medical Treatment of Lower Urinary Tract Symptoms with Finasteride
Lovastatin doesn't improve lower urinary tract symptoms treatment.
research Mild-Temperature Photothermal Assisted CuSi Nanowires for Promoting Infected Wound Healing
CuSi nanowires with NIR photothermal properties could effectively treat infected wounds and promote healing.
research Psoriasis Treatment in Difficult Locations: Scalp, Nails, and Intertriginous Areas
Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Rat Steroid 5α-Reductase Kinetic Characteristics: Extreme pH-Dependency of the Type II Isozyme in Prostate and Epididymis Homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Thallium Poisoning: Diagnosis May Be Elusive But Alopecia Is The Clue
Alopecia is a key indicator of thallium poisoning.