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    Glossary Skin Tumor

    A skin tumor is an abnormal growth of tissue on the skin, which can be benign (non-cancerous) or malignant (cancerous). In the context of hair loss, certain skin tumors, such as basal cell carcinoma or squamous cell carcinoma, can affect the scalp and disrupt hair follicles, potentially leading to hair thinning or loss in the affected areas. Key distinguishing characteristics of skin tumors include their appearance, size, and growth rate, as well as any associated symptoms like itching or bleeding. Early detection and treatment are crucial to prevent complications and preserve hair health.

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    1. Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours Development · 2002 · 297 citations
    2. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    3. CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice Cancer Research · 2007 · 141 citations
    4. Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development Oncogene · 1998 · 136 citations
    5. Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation Cancer research · 2009 · 49 citations
    6. Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8‐expressing transgenic mice The FASEB Journal · 2004 · 49 citations
    7. Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA‐1 expression Journal of Cutaneous Pathology · 2014 · 47 citations
    8. Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression Cell Reports · 2013 · 15 citations
    9. Tumor Promotion in Skin: Are Active Oxygen Species Involved? Elsevier eBooks · 1985 · 10 citations
    10. Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt<sup>WT</sup> mice Molecular carcinogenesis · 2013 · 8 citations
    11. Sox9 expression in canine epithelial skin tumors European journal of histochemistry · 2015 · 8 citations
    12. Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors Oncotarget · 2016 · 7 citations
    13. Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis Life science alliance · 2020 · 5 citations
    14. Treatment with Light-Emitting Diodes of Wavelength 863 nm Delays DMBA/TPA-Induced Skin Tumor Formation and Decreases Proinflammatory Cytokine Levels in ICR Mice BioMed Research International · 2022 · 2 citations
    15. Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients 2023
    16. The role of Kindlin-1 in skin homeostasis and tumor development Max Planck Digital Library · 2014
    17. Abstract 5202: Bone marrow-derived epithelial cells contribute to chronic skin inflammation and skin tumor formation in the mouse Cancer Research · 2012
    18. Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice Cancer research · 2014
    19. Antitumor Activities of the Typhonium flagelliforme Extract Combined with Natural Interferons of Canine and Feline in Mice with DMBA Induced Skin Tumors jurnal veteriner · 2023
    20. Histopathological Study of Epithelial, Melanocytic And Adnexal Tumors Of Skin- A Retrospective Study In A Tertiary Care Centre Annals of pathology and laboratory medicine · 2021
    21. ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS DigtalCommons @ Texas Medical Center Library (Texas Medical Center) · 2012
    22. Sertolioma in a Canadian Husky: Relationship between Tumor, Hormones, Neurons and Skin Acta Scientiae Veterinariae · 2019
    23. Genetic architecture of mouse skin inflammation and tumour susceptibility Nature · 2009 · 133 citations
    24. The Vitamin D Receptor as Tumor Suppressor in Skin Advances in experimental medicine and biology · 2020 · 55 citations
    25. Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors Oncotarget · 2016 · 8 citations
    26. Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis Stem cell reviews and reports · 2022 · 7 citations
    27. The genetic evolution of skin squamous cell carcinoma: tumor suppressor identity matters Experimental Dermatology · 2016 · 6 citations
    28. Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours Stem cells international · 2019 · 3 citations
    29. Histopathological analysis of skin adnexal tumors at tertiary care hospital International Journal of Clinical and Diagnostic Pathology · 2025
    30. Benign skin tumors 2016