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In this study, researchers found that the protein Twist2 plays a crucial role in scarless wound healing in early embryonic mouse skins, with its knockdown leading to visible scarring and defective hair follicle formation, suggesting potential therapeutic targets for reducing scars and promoting regeneration.

This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.

This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.

This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.

This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.

In this animal study, treatment with Trachyspermum copticum seed extract significantly altered IL-1 and KGF/FGF-7 gene expression, improving dermatitis and hair growth in mice compared to controls and corticosteroids.

This review examines the skin exposome, including solar exposure, air pollution, hormones, nutrition, and psychological factors, but reports no new clinical results.

This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.

This study found that lower serum melatonin levels were associated with increased skin aging grades among individuals in Ulaanbaatar, suggesting melatonin loss may contribute to earlier skin aging.

This review discusses mesenchymal stem cells' role in tissue regeneration and skin anti-aging, highlighting their migration to damaged sites and secretome effects, but reports no new clinical results.

This study explores the complex mechanisms of skin aging, including cellular senescence and disrupted communication, and highlights rejuvenation strategies like gene expression rewiring and microbiome modulation, offering potential frameworks for regenerative therapies and precise interventions in skin and systemic aging.

This narrative review explores how psychological stress may contribute to premature skin aging by affecting dermal collagen and elastin remodeling through neuroendocrine, molecular, and cellular pathways, highlighting potential therapeutic targets to preserve skin structure and function.

This review highlights research reporting that oral collagen peptide supplements are effective in enhancing skin elasticity, hydration, and reducing wrinkles, although results vary across studies. Oral supplementation was generally well-tolerated, and further investigation is needed to optimize formulations and explore topical application challenges.

This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.

This systematic review found that exosome-based therapies significantly improve skin elasticity, reduce wrinkle depth, enhance hydration, and modulate pigmentation, with minimal adverse events reported across multiple studies. However, further clinical trials are necessary to confirm long-term efficacy and safety.

Olive leaf extract may help reduce aging signs in postmenopausal women.

This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.

This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.

This study suggests that while platelet-rich products show promise in treating dermatological conditions like chronic wounds and skin aging, there is still a need for standardized methodologies and extensive trials to confirm their long-term clinical benefits.

This study found that downregulation of EGF and KGF signaling is necessary for hair follicle initiation in placodes, revealing a new role for KGF in hair follicle formation in mice.

This review discusses various skin lesions associated with endocrinologic disorders such as Cushing's syndrome and adrenal insufficiency, and it reports no new clinical results.

This article reviews the skin condition myxedema associated with hypothyroidism, highlighting its characteristic non-pitting, glycosaminoglycan-rich nature, and reports no new results.

This review discusses the classic skin characteristics of hypothyroidism, notably generalized myxedema caused by increased glycosaminoglycan deposition, and reports no clinical results.

This study reports that the tetrapeptide AcSDKP significantly promotes skin and hair health in vitro and ex vivo, suggesting it could be used cosmetically to counteract skin aging and hair loss.

This minireview discusses the mechanisms of facial aging, examines current literature, and proposes filler injection protocols, but it reports no new clinical results.

This source underscores the need for a multidisciplinary effort to raise awareness of Demodex and demodicosis, suggesting that prioritizing research, diagnostics, and treatment development could enhance global health outcomes and improve quality of life for affected individuals.

This chapter provides an overview of skin physiology, aging effects, and how environmental factors like UV damage impact skin health, without presenting new research findings.

In this cross-sectional study of healthy urban women in Shanghai, poor sleep quality and elevated perceived stress were linked to various self-reported dermatological issues and clinical signs, reinforcing the potential relevance of psychological factors in skin health.

This review highlights that effective management of PCOS-related dermatological issues, such as hirsutism and acne, requires a multidisciplinary approach involving hormonal therapies, metabolic interventions, and lifestyle changes.

This review explores how various skin cell types contribute to photoaging driven by UV radiation, detailing their interactions and molecular mechanisms like oxidative stress and ECM degradation, ultimately offering insights for future anti-photoaging strategies.