11 citations
,
June 2024 in “Clinical ophthalmology” This study highlights that Demodex mites, commonly found on human skin, can cause significant eye and skin issues such as blepharitis, rosacea, and dermatitis when present in abnormally high densities, underscoring the need for targeted management strategies.
35 citations
,
February 2023 in “Journal of Clinical Medicine” This review discusses treatments for demodicosis in adults and children and provides no new clinical results; the authors emphasize the need for careful diagnosis and therapy selection.
24 citations
,
August 2022 in “Immunity” This study found that control of Demodex mite colonization in mice required skin ILC2s and IL-13, highlighting their role in maintaining HF integrity and limiting mite overgrowth.
March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology” This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.
29 citations
,
August 2020 in “Parasitology” This review found that tea tree oil, especially terpinen-4-ol, may be the most effective treatment for Demodex-related diseases, but more research is needed to improve treatment efficacy and reduce side effects.
15 citations
,
March 2016 in “The American Journal of Dermatopathology” In this study, Demodex mites were infrequently found in scalp biopsies performed for hair loss, and most cases were nonpathogenic, but a minority showed folliculitis with a strong response to metronidazole therapy.
83 citations
,
August 2014 in “PLoS ONE” This study suggests that Demodex mites might universally inhabit adult humans, with a phylogenetic analysis indicating potential undiscovered lineages of the D. brevis species based on geographic differences.
81 citations
,
February 2014 in “Clinics in dermatology” This review discusses the potential role of Demodex mites in various human skin conditions, including acneiform eruptions and folliculitis, but reports no new research findings.
12 citations
,
January 2008 in “Indian Journal of Dermatology” This study found no significant relationship between Demodex infestation and androgenetic alopecia in male patients aged 20 to 40.
172 citations
,
December 2004 in “Journal of The American Academy of Dermatology” In this study, demodicoses were found to be relatively common among immunocompetent patients, with a notable overlap with papulopustular rosacea.
36 citations
,
March 2004 in “AIDS” This case report highlights that immune reconstitution after starting HAART can lead to demodex folliculitis in HIV patients, emphasizing the need to consider it in differential diagnosis of skin eruptions.
10 citations
,
June 1998 in “International Journal of Dermatology” This article discusses inflammatory perifollicular fibrosis and alopecia but provides no new research findings.
46 citations
,
January 1988 in “PubMed” This study found that Demodex mites may transport Microsporum canis spores on human skin, suggesting a potential role in microbial movement despite typically being considered harmless.