Evaluation of the Relationship Between Androgenetic Alopecia and Demodex Infestation

January 2008 in “ Indian Journal of Dermatology ”

Javidi Zari, Fata Abdolmajid, Maleki Masood, Mashayekhi Vahid, Nahidi Yalda

androgenetic alopecia Demodex infestation hair loss greasy hair Hamilton scale AGA baldness

Studysummary This study found no significant relationship between Demodex infestation and androgenetic alopecia in male patients aged 20 to 40.

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Research cited in this study

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research Genetic Basis of Male Pattern Baldness

191 citations , December 2003 in “Journal of Investigative Dermatology”

Male pattern baldness is largely genetic, linked to the androgen receptor gene, and may relate to certain health issues.

research Finasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins

15 citations , April 2002 in “PubMed”

In this study, finasteride significantly improved hair growth and patient satisfaction in men with male pattern hair loss compared to placebo, with no drug-related adverse events reported.

research Androgenetic Alopecia: The Role of Inflammation and Demodex

13 citations , July 2001 in “International Journal of Dermatology”

Inflammation and Demodex mites might contribute to hair loss, and targeting them could help treat it.

research Androgenetic Alopecia and Microinflammation

131 citations , August 2000 in “International Journal of Dermatology”

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

research Management of Androgenetic Alopecia

22 citations , May 2000 in “American Journal of Clinical Dermatology”

This review discusses treatment options for androgenetic alopecia in men and women, highlighting minoxidil and finasteride, without presenting new clinical findings.

research Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes

169 citations , June 1998 in “Journal of Investigative Dermatology”

This study found no significant genetic association between the 5α-reductase enzyme genes and male pattern baldness, suggesting a polygenic etiology rather than simple inheritance.

research Inflammatory Perifollicular Fibrosis And Alopecia

10 citations , June 1998 in “International Journal of Dermatology”

This article discusses inflammatory perifollicular fibrosis and alopecia but provides no new research findings.

research Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women

234 citations , December 1996 in “Journal of The American Academy of Dermatology”

The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.

research Management of Hair Loss in Women

29 citations , January 1993 in “Dermatologic Clinics”

This paper reviews diffuse androgen-dependent alopecia and chronic telogen effluvium in women, highlighting diagnostic challenges and management issues, but reports no new clinical findings; the authors suggest effective treatments are available.

research Cutaneous Immunopathology of Androgenetic Alopecia

10 citations , August 1991 in “PubMed”

This study supports the idea that inflammation may play a role in the development of androgenetic alopecia, as indicated by certain immune deposits and porphyrins found more frequently in bald scalp biopsies compared to controls.

research Histologic Response to Topically Applied Minoxidil in Male-Pattern Alopecia

38 citations , October 1988 in “Clinics in Dermatology”

Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.

research Male Pattern Alopecia: A Histopathologic and Histochemical Study

94 citations , August 1975 in “Journal of Cutaneous Pathology”

In this study, the researchers observed that male pattern alopecia is characterized by miniature follicles, enlarged sebaceous glands, and an increased number of mast cells, without significant abnormalities in enzyme activity.