13 citations
,
January 2016 in “Burns & Trauma” This review discusses the effects of vacuum massage on skin structures and concludes that there is insufficient evidence for its efficacy in treating burn scars, suggesting more research is needed on its potential benefits and mechanisms.
March 2026 in “European Journal of Biomedical and Life Sciences” This study highlights restorative dermopigmentation as a growing field in aesthetic medicine, aiming to address skin concerns like alopecia and age-related pigment loss by improving aesthetic and structural dermal deficits.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
122 citations
,
April 2020 in “American Journal Of Pathology” This review discusses the multiple factors contributing to skin aging, including cellular changes and environmental influences, and highlights its recognition as a disease with significant implications beyond cosmetic concerns, without reporting new research results.
70 citations
,
July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
16 citations
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July 2021 in “Histopathology” This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
1235 citations
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December 2013 in “Nature” This study found that skin fibroblasts in mice arise from two distinct lineages which contribute differently to dermal structure and repair, impacting hair follicle formation during wound healing.
21 citations
,
November 2010 in “Journal of molecular medicine” This study found that deleting FoxN1 in specific thymic epithelial cells disrupted the 3D thymic structure and led to age-dependent formation of 2D epithelial cysts, highlighting FoxN1's critical role in thymic morphogenesis.
December 2025 in “The Journal of Basic and Applied Zoology” This study found that the prenatal skin development in Red Sokoto goats undergoes significant morphological changes across gestational stages, which may be important for their adaptation and thermoregulation after birth.
2 citations
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July 2017 in “IEEE Photonics Journal” This study found that combining second-harmonic generation with optical coherence tomography may effectively evaluate wound healing by monitoring collagen formation and optical signal changes in regenerated tissue.
January 2025 in “Medical Research Archives” This review discusses the crucial role of sex hormones in maintaining and influencing skin health, suggesting ongoing research into hormonal treatments for skin conditions due to life stage changes.
31 citations
,
November 2016 in “Cell Reports” This study reveals that somatosensory neurons in mouse skin exhibit structural plasticity during hair-follicle regeneration, which may temporarily impair the reliability of encoding gentle touch.
2 citations
,
August 2024 in “JID Innovations” This study suggests that keratinocytes derived from hair follicles of patients with atopic dermatitis provide a useful model for investigating AD-related inflammation, as they showed greater expression changes of AD markers when stimulated with type 2 cytokines compared to those from healthy donors.
April 2023 in “Journal of Investigative Dermatology” The study identified increased IL-24 expression in keratinocytes and fibroblasts exposed to particulate matter, contributing to skin aging by promoting conditions similar to age-related changes such as increased MMP1 expression and decreased type I collagen production.
79 citations
,
August 1998 in “The Journal of Cell Biology” In a transgenic mouse model, this study found that overexpression of keratin 16 in skin keratinocytes led to hyperkeratosis and increased EGF receptor signaling, altering skin cell behavior and structure.
2 citations
,
February 2018 This study found that Raman spectroscopy has potential for detecting biophysical differences in basal cell carcinoma compared to normal skin structures, supporting its future use in Mohs surgery.
6 citations
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May 2020 in “Nutrients” This review discusses the effects of calorie restriction on skin aging, highlighting its potential to benefit skin health by reducing age-related and photo-induced changes, although the impact of certain diets remains unexplored.
7 citations
,
April 2014 in “Cell biology international” This study found that melatonin treatment increased epidermal thickness, subcutaneous fat, and dermal-related factors in postmenopausal rats, suggesting benefits for skin structure after menopause.
1 citations
,
April 2023 in “International journal of molecular sciences” In this study, AMACO was found to be non-essential for the formation or function of anchoring cords in mice, despite its presence in the structure.
This study found that the NuMA protein's microtubule-binding domain is essential for proper spindle orientation and differentiation in keratinocytes, affecting skin and hair development in mice.
5 citations
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February 2019 in “PloS one” This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.
3 citations
,
August 1992 in “Bulletin of Experimental Biology and Medicine” Diabetes changes keratin in skin and hair, affecting their health.
January 2026 in “Journal of Cosmetic Dermatology” This study reviewed evidence suggesting that the loss of dermal white adipose tissue (dWAT) during menopause may be linked to decreased estrogen levels, potentially affecting skin health, and discussed non-hormonal treatments, like magnolol, that might help restore dWAT and improve menopausal skin changes.
3 citations
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May 2011 in “Facial plastic surgery clinics of North America” This article reviews the causes and treatments of fine rhytids, highlighting the potential effectiveness of laser rejuvenation therapies but presents no new clinical results.
This study found that structural changes in the stroma surrounding hair follicles and skin laxity are associated with the appearance of large pores, regardless of ethnicity or age.
70 citations
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January 2014 in “International review of cell and molecular biology” This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.
159 citations
,
January 2006 in “BMC Cell Biology” This study found that manipulating Wnt signaling pathways in cutaneous wounds can induce skin structures resembling regeneration, suggesting a potential role for Wnt signals in restoring skin architecture during wound healing.
July 2024 in “Biological and Clinical Sciences Research Journal” This review reports that transgender individuals undergoing hormonal therapy for gender transition face increased risks of cardiovascular disorders, brain tumors, changes in bone density, metabolic disorders, and other health issues, while highlighting the necessity of this therapy for gender transformation.
24 citations
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February 2004 in “Plastic & Reconstructive Surgery” This book provides a comprehensive guide to cosmetic dermatology, emphasizing practical applications of skin care in cosmetic and surgical practices, but it reports no new clinical findings.