117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
2 citations,
September 2018 in “Tissue Engineering Part A” Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.
321 citations,
March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
39 citations,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
93 citations,
October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
3 citations,
September 2023 in “Skin research and technology” New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
August 2023 in “Stem Cell Research & Therapy” A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.
59 citations,
September 2008 in “Journal of Burn Care & Research” Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
15 citations,
January 2014 in “BioMed Research International” Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
43 citations,
November 2013 in “Journal of Investigative Dermatology” Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
48 citations,
July 2019 in “International Journal of Biological Macromolecules” A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
15 citations,
February 2009 in “Cell Stem Cell” The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.
3 citations,
July 2020 in “Frontiers in Cell and Developmental Biology” Vitexin Compound 1 may help reduce skin aging caused by UVA light.
59 citations,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
9 citations,
March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
384 citations,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
28 citations,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
10 citations,
December 2021 in “Frontiers in cell and developmental biology” The research identified genes that explain why some sheep have curly wool and others have straight wool.
8 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
8 citations,
December 2015 in “The Journal of Physiology” The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.
2 citations,
May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
54 citations,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
13 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.
6 citations,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
3 citations,
September 2018 in “Journal of Biomaterials Science, Polymer Edition” Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.