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Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Using neurohormones to control keratin can lead to new skin disease treatments.

Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Cannabinoids may help treat various skin conditions.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

Skin aging reflects overall body aging and can indicate internal health conditions.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Hair follicles prevent NK cell attacks to avoid hair loss.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.

The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Researchers created human hair follicles using a new method that could help treat hair loss.

Increasing sebum production might help reduce fat and improve metabolism.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.