research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
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research Hair-Follicle Dermal Papilla and Sheath Fibroblasts Provide a Supportive Microenvironment for Human Skin Regeneration
Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Predominant Expression of 5 Alpha-Reductase Type 1 in Pubic Skin from Normal Subjects and Hirsute Patients
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity
Scientists identified a unique type of human skin stem cell that could help with tissue repair.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Human Dermal Stem Cells Differentiate Into Functional Epidermal Melanocytes
Human dermal stem cells can become functional skin pigment cells.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Serotoninergic And Melatoninergic Systems Are Fully Expressed In Human Skin
Human skin can make serotonin and melatonin.
research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
research Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration
Hydrogel microcapsules help create cells that boost hair growth.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Sustained Release of Dermal Papilla-Derived Extracellular Vesicles from Injectable Microgel Promotes Hair Growth
Injecting a special gel with human protein particles can help hair grow.
research Experimental Assessment of Regenerative Properties of Platelet-Rich Plasma on Human Skin: A Review
PRP helps skin regeneration but needs standardized testing for consistent results.
research Regulatory T Cells in Skin Regeneration and Wound Healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research Nanotechnology-Based Techniques for Hair Follicle Regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair
Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.