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Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Human skin has less GDNF and its receptor with age.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.

Notch signaling disruptions can cause various skin diseases.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

TGM3 is important for skin and hair structure and may help diagnose cancer.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

OR2AT4 helps reduce aging and cell damage in human skin cells.

Retinoic acid affects male and female muscle energy use and function differently.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

Hair transplantation successfully treated hair loss in a patient with Trichorhinophalangeal syndrome.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

PRP helps skin heal, possibly through special cells called telocytes.

Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.

Women with Polycystic Ovary Syndrome (PCOS) have a higher risk of developing type 2 diabetes due to insulin resistance.

Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.

Human dermal stem cells can become functional skin pigment cells.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Fatp4 is crucial for healthy skin development and function.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Vitamin D is crucial for bone health and preventing serious diseases.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.